Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8347636 | 0.86 | CYP2D6 (0.46) | CYP2D6SMN1; SMN2MEN1CYP1A2CYP2C9 | |
| SCHEMBL9069600 | 0.84 | CYP1A2 (0.39) | SMN1; SMN2MEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12933360 | 0.78 | CYP2D6 (0.43) | CYP2D6SMN1; SMN2MEN1CYP1A2CYP2C9 | |
| SCHEMBL28980714 | 0.78 | BCHE (0.40) | CYP1A2CYP2C9CYP2C19TP53RAB9A | |
| SCHEMBL20878242 | 0.76 | CYP2D6 (0.44) | CYP2D6SMN1; SMN2MEN1CYP1A2CYP2C9 | |
| SCHEMBL17923288 | 0.76 | CES2 (0.40) | CYP2D6MEN1KMT2ANPC1RAB9A | |
| SCHEMBL3994733 | 0.73 | CYP2D6 (0.55) | CYP2D6MEN1CYP1A2KMT2APARP3 | |
| SCHEMBL10786114 | 0.72 | MEN1 (0.43) | CYP2D6SMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL11636473 | 0.72 | MEN1 (0.43) | CYP2D6SMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL11636480 | 0.72 | MEN1 (0.43) | CYP2D6SMN1; SMN2MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115932126-A | Detection method for measuring racemization-3-n-butylphthalide related substances by HPLC | 河北菲尼斯生物技术有限公司 | 2023-04-07 | — | — | CN | claimed |
| CN-115901976-A | Detection method for measuring 3-butyl-1 (3H) -isobenzofuranone related substances by adopting HPLC | 河北菲尼斯生物技术有限公司 | 2023-04-04 | — | — | CN | claimed |
| CN-115932126-A | Detection method for measuring racemization-3-n-butylphthalide related substances by HPLC | 河北菲尼斯生物技术有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-115932126-A | Detection method for measuring racemization-3-n-butylphthalide related substances by HPLC | 河北菲尼斯生物技术有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-115901976-A | Detection method for measuring 3-butyl-1 (3H) -isobenzofuranone related substances by adopting HPLC | 河北菲尼斯生物技术有限公司 | 2023-04-04 | — | — | CN | disclosed |
| US-7868204-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2011-01-11 | — | — | US | disclosed |
| US-7838520-B2 | Inhibitors of histone deacetylase | METHYLGENE, INC. (CA) | 2010-11-23 | — | — | US | disclosed |
| US-7595343-B2 | Inhibitors of histone deacetylase | METHYLGENE, INC. (CA) | 2009-09-29 | — | — | US | disclosed |