SCHEMBL1296409

SCHEMBL1296409

CCOC(=O)C1CCC(C(=O)O)CC1

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PPM1B O75688 1/20 0.55
PTPN1 P18031 1/20 0.55
PPP1CC P36873 1/20 0.55
MAPT P10636 2/20 0.53
ALDH1A1 P00352 4/20 0.50
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
KDM4E B2RXH2 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
PKM P14618 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8485910 1.00 PPM1B (0.55) PPM1BPTPN1PPP1CCMAPTALDH1A1
Ethylene Glycol SCHEMBL1297415 0.94 PPM1B (0.50) PPM1BPTPN1PPP1CCMAPTALDH1A1
SCHEMBL4221 0.91
SCHEMBL2375356 0.91 MAPT (0.60) PPM1BPTPN1PPP1CCMAPTALDH1A1
SCHEMBL8891623 0.91 MAPT (0.60) PPM1BPTPN1PPP1CCMAPTALDH1A1
SCHEMBL237380 0.91 MAPT (0.60) PPM1BPTPN1PPP1CCMAPTALDH1A1
SCHEMBL28405366 0.90 ALDH1A1 (0.63) PPM1BPTPN1PPP1CCMAPTALDH1A1
SCHEMBL29291438 0.90 ALDH1A1 (0.63) PPM1BPTPN1PPP1CCMAPTALDH1A1
Hydrochloric Acid SCHEMBL28788727 0.89
SCHEMBL31196227 0.88 PPM1B (0.47) PPM1BPTPN1PPP1CCMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5030771-A Heating and pressurization in the presence of a copper chromite catalyst HUELS AKTIENGESELLSCHAFT (DE) 1991-07-09 US claimed
WO-2023220425-A1 BCL-XL/BCL-2 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. (US) 2023-11-16 WO disclosed
CN-107840908-B Solid catalyst component for olefin polymerization, catalyst system and prepolymerization catalyst 中国石油化工股份有限公司 2020-11-10 CN disclosed
CN-107840915-B Solid catalyst component for olefin polymerization, catalyst system and prepolymerization catalyst 中国石油化工股份有限公司 2020-11-10 CN disclosed
CN-107840916-B Solid catalyst component for olefin polymerization, catalyst system and prepolymerization catalyst 中国石油化工股份有限公司 2020-11-10 CN disclosed
CN-107840905-B Solid catalyst component for olefin polymerization, catalyst system and prepolymerization catalyst 中国石油化工股份有限公司 2020-04-07 CN disclosed
US-8889748-B2 Process for producing expandable styrene polymer compositions BASF SE (DE) 2014-11-18 US disclosed
US-8535436-B2 Use of cyclohexane polycarboxylic acid derivatives for removing dust from chemical construction products CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2013-09-17 US disclosed
US-8454744-B2 Use of polyols and cyclohexane polycarboxylic acid derivatives for the removal of dust from chemical construction products CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2013-06-04 US disclosed
US-20120138206-A1 ADHESIVES AND SEALANTS CONTAINING CYCLOHEXANE POLYCARBOXYLIC ACID DERIVATIVES BASF SE (DE) 2012-06-07 US disclosed
CN-1241882-C Method for hydrogenating organic compounds by means of RU/SIO2 catalysts BASF AG (DE) 2006-02-15 CN disclosed
US-20050106405-A1 Single piece closure device made of pvc BASF AKTIENGESELLSCHAFT (DE) 2005-05-19 US disclosed
US-6809101-B2 RNA POLYMERASES INHIBITORS; SUCH AS 5-(1-HYDROXY-1-(5-METHYL-OXAZOL-2-YL))METHYLENE-2-THIOXOTHIAZOLIDIN-4-ONE SHIONOGI & CO., LTD. (JP) 2004-10-26 US disclosed
CN-1531459-A With Ru/SiO2Method for hydrogenating organic compounds with a catalyst �����ɷ� 2004-09-22 CN disclosed
US-20030203948-A1 Compounds having anti-hepatitics c virus effect Z-KAT, INC. 2003-10-30 US disclosed
US-5614486-A DIETHYL 1,4-CYCLOHEXANEDICARBOXYLATE FIRMENICH SA (CH) 1997-03-25 US disclosed
US-5607944-A ANTICOAGULANTS KARL THOMAE GMBH (DE) 1997-03-04 US disclosed
US-5030771-A Heating and pressurization in the presence of a copper chromite catalyst HUELS AKTIENGESELLSCHAFT (DE) 1991-07-09 US disclosed
US-4151152-A POLYESTERURETHANES, SHELF LIFE VEBA-CHEMIE AKTIENGESELLSCHAFT (DE) 1979-04-24 US disclosed
US-4024173-A Process for the manufacture of cyclohexene dicarboxylic acid esters DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1977-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030203948-A1 Compounds having anti-hepatitics c virus effect NSUN3, HCCS, NSUN2 PPM1B 3350/4885PTPN1 1800/4885PPP1CC 3505/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.