Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7864094 | 0.98 | KCNH2 (0.49) | IGF1RALOX15AOC3KCNH2TAAR1 | |
| SCHEMBL14415406 | 0.94 | MAOB (0.48) | IGF1RALOX15AOC3KCNH2TAAR1 | |
| SCHEMBL9146183 | 0.94 | AOC3 (0.48) | IGF1RALOX15AOC3KCNH2TAAR1 | |
| SCHEMBL436099 | 0.85 | AOC3 (0.52) | AOC3KCNH2TAAR1SLC6A2SLC6A3 | |
| Hydrogen Peroxide SCHEMBL29262757 | 0.83 | GRIN2D (0.49) | SLC6A2SLC6A3 | |
| Ammonia Solution, Strong SCHEMBL10725614 | 0.83 | AOC3 (0.50) | AOC3KCNH2TAAR1SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL27666375 | 0.83 | AOC3 (0.50) | AOC3KCNH2TAAR1SLC6A2SLC6A3 | |
| SCHEMBL10365734 | 0.82 | IGF1R (0.64) | IGF1RALOX15AOC3KCNH2TAAR1 | |
| SCHEMBL28966782 | 0.79 | IGF1R (0.61) | IGF1RALOX15AOC3KCNH2TAAR1 | |
| SCHEMBL1115439 | 0.79 | IGF1R (0.61) | IGF1RALOX15AOC3KCNH2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012135027-A2 | THIOLACTONE ANTIBIOTICS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2012-10-04 | — | — | WO | disclosed |