Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.55 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.52 |
| ▸ | HTR3B | O95264 | 1/20 | 0.52 |
| ▸ | HTR3A | P46098 | 1/20 | 0.52 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.52 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28966782 | 1.00 | IGF1R (0.61) | IGF1RALOX15TAAR1KCNH2HDAC3 | |
| SCHEMBL10365734 | 0.97 | IGF1R (0.64) | IGF1RALOX15TAAR1KCNH2HDAC3 | |
| SCHEMBL18050371 | 0.91 | TAAR1 (0.62) | IGF1RALOX15TAAR1KCNH2HDAC3 | |
| SCHEMBL12040532 | 0.90 | MAOB (0.58) | IGF1RALOX15KCNH2MAOBGPR84 | |
| SCHEMBL8723191 | 0.90 | MAOB (0.58) | IGF1RALOX15KCNH2MAOBGPR84 | |
| SCHEMBL11460578 | 0.88 | KCNH2 (0.53) | IGF1RALOX15TAAR1KCNH2HDAC3 | |
| SCHEMBL10610818 | 0.88 | IGF1R (0.52) | IGF1RALOX15TAAR1KCNH2HDAC3 | |
| SCHEMBL11400125 | 0.88 | IGF1R (0.52) | IGF1RALOX15TAAR1KCNH2HDAC3 | |
| SCHEMBL11353612 | 0.88 | IGF1R (0.52) | IGF1RALOX15TAAR1KCNH2HDAC3 | |
| SCHEMBL11335508 | 0.88 | TAAR1 (0.67) | IGF1RALOX15TAAR1KCNH2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373237-B1 | METHODS FOR PRODUCING OXIRANE CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | MEDIGENE AG (DE) | 2011-02-02 | — | — | EP | disclosed |
| US-7078543-B2 | Methods for producing oxirane carboxylic acids and derivatives thereof | MEDIGENE AKTIENGESELLSCHAFT (DE) | 2006-07-18 | — | — | US | disclosed |
| US-20040236103-A1 | Methods for producing oxirane carboxylic acids and derivatives thereof | MEDIGENE AKTIENGESELLSCHAFT (DE) | 2004-11-25 | — | — | US | disclosed |
| EP-1373237-A1 | METHODS FOR PRODUCING OXIRANE CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | MediGene Aktiengesellschaft (DE) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002079178-A1 | METHODS FOR PRODUCING OXIRANE CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | MEDIGENE AKTIENGESELLSCHAFT (DE) | 2002-10-10 | — | — | WO | disclosed |
| US-4834905-A | LIQUID CRYSTAL DIELECTRICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-05-30 | — | — | US | disclosed |
| US-4627933-A | ESTERS, ETHERS, NITRICES, HALIDES, OR HYDROCARBONS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1986-12-09 | — | — | US | disclosed |
| EP-0104327-A2 | Use of cyclic derivatives as components of liquid cristals | MERCK PATENT GmbH (DE) | 1984-04-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040236103-A1 | Methods for producing oxirane carboxylic acids and derivatives thereof | ACSL5, HSD17B12, COASY | IGF1R 3016/4885ALOX15 56/4885TAAR1 2553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.