Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 17/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12870218 | 0.89 | MET (0.48) | METNQO2 | |
| SCHEMBL12870143 | 0.86 | MET (0.46) | METNQO2 | |
| SCHEMBL12870220 | 0.81 | MET (0.51) | METNQO2 | |
| SCHEMBL12870219 | 0.80 | MET (0.51) | METNQO2 | |
| SCHEMBL1151835 | 0.80 | MET (0.51) | METNQO2 | |
| SCHEMBL29550022 | 0.76 | MET (0.63) | METNQO2 | |
| SCHEMBL1296500 | 0.76 | MET (0.63) | METNQO2 | |
| SCHEMBL12857965 | 0.75 | MET (0.37) | METNQO2 | |
| SCHEMBL12240559 | 0.73 | MET (0.51) | METNQO2 | |
| SCHEMBL12760969 | 0.73 | MET (0.78) | METNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2280962-B1 | PYRIDAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2012-10-03 | — | — | EP | disclosed |