SCHEMBL1297157

SCHEMBL1297157

CCCCC(CC)COCCOC(=O)C1CCCCC1C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MMP9 P14780 1/20 0.51
MMP8 P22894 1/20 0.51
MMP14 P50281 1/20 0.51
CYP3A4 P08684 5/20 0.46
TSHR P16473 3/20 0.42
ATM Q13315 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ALDH1A1 P00352 5/20 0.40
CA2 P00918 1/20 0.38
RECQL P46063 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
LMNA P02545 3/20 0.35
MAPK1 P28482 2/20 0.34
HSD17B10 Q99714 1/20 0.34
NCOA1 Q15788 1/20 0.34
NCOA3 Q9Y6Q9 1/20 0.34
PRSS1 P07477 1/20 0.34
PRSS2 P07478 1/20 0.34
PRSS3 P35030 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9945515 0.95 MMP9 (0.52) MMP9MMP8MMP14CYP3A4TSHR
SCHEMBL1297156 0.89 MMP9 (0.39) MMP9MMP8MMP14CYP3A4PRSS1
SCHEMBL1196552 0.89 CYP3A4 (0.50) MMP9MMP8MMP14CYP3A4TSHR
SCHEMBL22856171 0.88 CYP3A4 (0.47) MMP9MMP8MMP14CYP3A4TSHR
Ethylene Glycol SCHEMBL1297154 0.85 CYP3A4 (0.47) MMP9MMP8MMP14CYP3A4TSHR
SCHEMBL1297564 0.83 MMP9 (0.46) MMP9MMP8MMP14CYP3A4TSHR
SCHEMBL1296983 0.83 CYP3A4 (0.50) MMP9MMP8MMP14CYP3A4TSHR
SCHEMBL1296534 0.83 CYP3A4 (0.50) MMP9MMP8MMP14CYP3A4TSHR
SCHEMBL1142664 0.83 CYP3A4 (0.55) MMP9MMP8MMP14CYP3A4TSHR
SCHEMBL1297939 0.82 MMP9 (0.50) MMP9MMP8MMP14CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8454744-B2 Use of polyols and cyclohexane polycarboxylic acid derivatives for the removal of dust from chemical construction products CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2013-06-04 US disclosed
US-20120138206-A1 ADHESIVES AND SEALANTS CONTAINING CYCLOHEXANE POLYCARBOXYLIC ACID DERIVATIVES BASF SE (DE) 2012-06-07 US disclosed
US-20110265693-A1 Use Of Polyols And Cyclohexane Polycarboxylic Acid Derivatives For The Removal Of Dust From Chemical Construction Products Construction Research & Tecnology GMBH (DE) 2011-11-03 US disclosed
US-7337913-B2 Single piece closure device made of PVC BASF AKTIENGESELLSCHAFT (DE) 2008-03-04 US disclosed
US-20050106405-A1 Single piece closure device made of pvc BASF AKTIENGESELLSCHAFT (DE) 2005-05-19 US disclosed