Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | ESR1 | P03372 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | KDR | P35968 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | STS | P08842 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696080 | 0.88 | MAPT (0.62) | ALDH1A1TSHRESR1MAPTKMT2A | |
| SCHEMBL7690777 | 0.88 | MAPT (0.62) | ALDH1A1TSHRESR1MAPTKMT2A | |
| SCHEMBL26804085 | 0.87 | CA1 (0.58) | TSHRESR1MAPTKMT2AHPGD | |
| SCHEMBL19373814 | 0.86 | MAPT (0.70) | ALDH1A1TSHRESR1TDP1CHRM1 | |
| SCHEMBL7690507 | 0.84 | MAPT (0.58) | ALDH1A1TSHRESR1MAPTKMT2A | |
| SCHEMBL12987684 | 0.84 | MAPT (0.57) | ALDH1A1TSHRESR1TDP1CHRM1 | |
| SCHEMBL4644691 | 0.83 | ALDH1A1 (0.64) | ALDH1A1TSHRESR1TDP1CHRM1 | |
| SCHEMBL1988247 | 0.83 | TSHR (0.68) | ALDH1A1TSHRESR1TDP1CHRM1 | |
| SCHEMBL680463 | 0.83 | ALDH1A1 (0.72) | ALDH1A1TSHRESR1TDP1CHRM1 | |
| SCHEMBL49950 | 0.82 | ALDH1A1 (0.84) | ALDH1A1TSHRESR1TDP1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100311920-A1 | Using Reactive Block Copolymers as Chain Extenders and Surface Modifiers | CID CENTRO DE INVESTIGACION Y DESARROLLO TECNOLOGICO SA DE CV (MX) | 2010-12-09 | — | — | US | disclosed |