Tetrahydrofuran

Tetrahydrofuran

SCHEMBL129722

C1CCOC1.CN(C)C=O

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.53
ALDH1A1 P00352 1/20 0.47
ADH1C P00326 1/20 0.33
ADH1A P07327 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylformamide SCHEMBL1072443 0.97 TSHR (0.50) TSHRALDH1A1ADH1CADH1A
Tetrahydrofuran SCHEMBL28743802 0.97 TSHR (0.50) TSHRALDH1A1ADH1CADH1A
Tetrahydrofuran SCHEMBL2439396 0.95 TSHR (0.47) TSHRALDH1A1ADH1CADH1A
Tetrahydrofuran SCHEMBL16837095 0.92 TSHR (0.45) TSHRALDH1A1ADH1CADH1A
Tetrahydrofuran SCHEMBL10905548 0.92 TSHR (0.45) TSHRALDH1A1ADH1CADH1A
Tetrahydrofuran SCHEMBL23295002 0.90 TSHR (0.43) TSHRALDH1A1
Tetrahydrofuran SCHEMBL9660850 0.88 TSHR (0.41) TSHRALDH1A1
Dimethylformamide SCHEMBL11296326 0.88 TSHR (0.60) TSHRADH1CADH1A
Dioxane SCHEMBL1072446 0.88 TSHR (0.60) TSHRADH1CADH1A
Tetrahydrofuran SCHEMBL28212755 0.86 TSHR (0.39) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 739 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116023323-B Preparation method of avibactam intermediate 浙江工业大学 2025-06-17 CN claimed
CN-120058599-A Preparation method of acetophenone oxime hill-oriented reagent 广东医科大学 2025-05-30 CN claimed
CN-119391031-A Preparation method of PET-based composite copper foil 深圳市国钠科技有限公司 2025-02-07 CN claimed
CN-118496610-A Phosphorescent composite material based on benzoic acid derivative and polyvinyl alcohol, and preparation method and application thereof 天津师范大学 2024-08-16 CN claimed
CN-117815942-A Bionic nanofiber fuel filter membrane and preparation method thereof 浙江理工大学 2024-04-05 CN claimed
CN-117730904-A Fresh-keeping packaging and storing method and application special for low-voltage electrostatic field cooperation of new plums 中国农业科学院农产品加工研究所 2024-03-22 CN claimed
CN-115233500-B Sustained-release aromatic wallpaper and preparation method thereof 肖晓声 2024-01-30 CN claimed
CN-114507218-B Indole piperidine pyrimidine derivative and preparation method and application thereof 武汉工程大学 2024-01-16 CN claimed
CN-115043796-B Method for preparing tetrahydrofuran dicarboxamide and 2-hydroxy adipamide through hydrogenation of furan dicarboxamide 河北工业大学 2023-12-01 CN claimed
CN-116854582-A Preparation method of enantiomerically pure alpha-methoxyphenylacetic acid 泰州葛林美克医药科技有限公司 2023-10-10 CN claimed
US-20150158230-A1 SIMPLE DEVICE FOR ECONOMICALLY PRODUCING ELECTROSPUN FIBERS AT MODERATE RATES THE UNIVERSITY OF AKRON 2015-06-11 US claimed
CN-103756003-A Method for preparing polymer symmetrical porous membrane by complete evaporation method UNIV CHANGSHA SCIENCE 2014-04-30 CN claimed
CN-102827131-A Isoflavone carbamate compound, preparation method and applications of isoflavone carbamate compound UNIV SICHUAN 2012-12-19 CN claimed
EP-2010588-B1 Organosilicon polyurea polymers, elastomers manufactured therefrom and their use HENKEL AG & CO KGAA (DE) 2012-01-04 EP claimed
WO-2009116075-A2 PROCESS FOR PREPARATION OF TAZAROTENE INDOCO REMEDIES LIMITED (IN) 2009-09-24 WO claimed
EP-2010588-A1 ORGANOSILICON-POLYUREA BASE POLYMER, ELASTOMER PREPARED THEREFROM, PREPARATION THEREOF AND USE OF THE SAME Henkel AG & Co. KGaA (DE) 2009-01-07 EP claimed
CN-101209331-A Capsule preparations, preparation and quality control method thereof WENLONG YANG (CN) 2008-07-02 CN claimed
WO-2007118880-A1 ORGANOSILICON-POLYUREA BASE POLYMER, ELASTOMER PREPARED THEREFROM, PREPARATION THEREOF AND USE OF THE SAME HENKEL AG & CO. KGAA (DE) 2007-10-25 WO claimed
US-5395997-A Process for the preparation of hydrofluorocarbons having 3 to 7 carbon atoms ALLIEDSIGNAL INC. (US) 1995-03-07 US claimed
US-5096974-A Reacting primary amino or hydrazido-substituted stabilizers with maleic anhydride polymers; nonextractable and nonvolatile in polymer blends ATOCHEM NORTH AMERICA, INC. (US) 1992-03-17 US claimed