Dimethylformamide

Dimethylformamide

SCHEMBL11296326

C1COCCOCCOCCOCCOCCO1.CN(C)C=O

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.60
TTR P02766 1/20 0.40
ADH1C P00326 1/20 0.31
ADH1A P07327 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dioxane SCHEMBL1072446 1.00 TSHR (0.60) TSHRTTRADH1CADH1ASMN1; SMN2
Dioxane SCHEMBL271366 0.97 TSHR (0.56) TSHRTTR
Dimethylformamide SCHEMBL10559930 0.97
Dioxane SCHEMBL28817546 0.94 TSHR (0.53) TSHRTTRSMN1; SMN2
Dimethylformamide SCHEMBL23322519 0.88 TSHR (0.53) TSHR
Tetrahydrofuran SCHEMBL129722 0.88 TSHR (0.53) TSHRADH1CADH1A
Dioxane SCHEMBL6550359 0.87 TSHR (0.45) TSHRTTRSMN1; SMN2
Tetrahydrofuran SCHEMBL28743802 0.85 TSHR (0.50) TSHRADH1CADH1A
Dimethylformamide SCHEMBL1072443 0.85 TSHR (0.50) TSHRADH1CADH1A
Dioxane SCHEMBL16719050 0.84 TSHR (0.43) TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0061830-A1 Preparation of composite oxidation catalyst and use thereof for the production of unsaturated aldehydes and acids from propylene and isobutylene THE STANDARD OIL COMPANY (US) 1982-10-06 EP disclosed