Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP6 | P51161 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.48 |
| ▸ | MASP2 | O00187 | 1/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19216416 | 0.86 | PLAU (0.56) | FABP6KMT2AALDH1A1MEN1NUDT1 | |
| SCHEMBL29243709 | 0.80 | ALDH1A1 (0.44) | KMT2AALDH1A1MEN1EGFRTDP1 | |
| SCHEMBL4239810 | 0.79 | PRKD3 (0.47) | FABP6KMT2AALDH1A1MEN1NUDT1 | |
| SCHEMBL7901195 | 0.79 | KDM4E (0.55) | KMT2AALDH1A1MEN1TDP1MAPT | |
| SCHEMBL19243088 | 0.78 | MAPT (0.56) | KMT2AALDH1A1MEN1TDP1MAPT | |
| SCHEMBL14683901 | 0.76 | HPSE (0.50) | KMT2AALDH1A1MEN1TDP1MAPT | |
| SCHEMBL15457670 | 0.76 | ALDH1A1 (0.46) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL129665 | 0.76 | FABP6 (0.60) | FABP6KMT2AALDH1A1MEN1NUDT1 | |
| SCHEMBL118057 | 0.75 | MEN1 (0.57) | FABP6KMT2AALDH1A1MEN1NUDT1 | |
| SCHEMBL29449363 | 0.75 | MEN1 (0.57) | FABP6KMT2AALDH1A1MEN1NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010144686-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH BENZIMIDAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2010-12-16 | — | — | WO | disclosed |
| EP-1383731-B1 | BIARYL COMPOUNDS AS SERINE PROTEASE INHIBITORS | BIOCRYST PHARM INC (US) | 2009-08-05 | — | — | EP | disclosed |