Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 12/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12974664 | 0.90 | EPHX1 (0.56) | EPHX1HTTALDH1A1SMN1; SMN2ATM | |
| SCHEMBL10082872 | 0.90 | EPHX1 (0.56) | EPHX1HTTALDH1A1SMN1; SMN2ATM | |
| SCHEMBL10083506 | 0.88 | HTT (0.57) | EPHX1HTTALDH1A1SMN1; SMN2ATM | |
| SCHEMBL10068140 | 0.88 | EPHX1 (0.53) | EPHX1HTTALDH1A1SMN1; SMN2ATM | |
| SCHEMBL10068151 | 0.86 | HTT (0.54) | EPHX1HTTALDH1A1SMN1; SMN2ATM | |
| SCHEMBL10463823 | 0.85 | SMN1; SMN2 (0.63) | EPHX1HTTALDH1A1SMN1; SMN2ATM | |
| SCHEMBL2361098 | 0.82 | HTT (0.91) | EPHX1HTTALDH1A1SMN1; SMN2ATM | |
| SCHEMBL6438910 | 0.79 | EPHX1 (0.83) | EPHX1HTTALDH1A1EPHX2 | |
| SCHEMBL6442708 | 0.79 | EPHX1 (0.73) | EPHX1HTTALDH1A1EPHX2 | |
| SCHEMBL11033138 | 0.78 | EPHX1 (0.84) | EPHX1HTTALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7857962-B2 | Potentiometric electrode, gradient polymer, uses and method of preparation therefor | UNIVERSITEIT ANTWERPEN (BE) | 2010-12-28 | — | — | US | disclosed |