Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10068140 | 0.99 | EPHX1 (0.53) | HTTSMN1; SMN2EPHX1ALDH1A1ATM | |
| SCHEMBL10068142 | 0.91 | EPHX1 (0.49) | HTTSMN1; SMN2EPHX1ATMNPC1 | |
| SCHEMBL12974657 | 0.86 | EPHX1 (0.63) | HTTSMN1; SMN2EPHX1ALDH1A1ATM | |
| SCHEMBL10068162 | 0.82 | PIK3CG (0.45) | HTTSMN1; SMN2ALDH1A1RAB9APOLB | |
| SCHEMBL77586 | 0.81 | NPC1 (0.49) | SMN1; SMN2ALDH1A1NPC1RAB9APOLB | |
| SCHEMBL10083506 | 0.81 | HTT (0.57) | HTTSMN1; SMN2EPHX1ALDH1A1ATM | |
| SCHEMBL10068163 | 0.81 | MAPK13 (0.57) | SMN1; SMN2EPHX1ALDH1A1NPC1RAB9A | |
| SCHEMBL10082138 | 0.80 | EPHX1 (0.47) | HTTSMN1; SMN2EPHX1ATMNPC1 | |
| SCHEMBL10082872 | 0.80 | EPHX1 (0.56) | HTTSMN1; SMN2EPHX1ALDH1A1ATM | |
| SCHEMBL12974664 | 0.80 | EPHX1 (0.56) | HTTSMN1; SMN2EPHX1ALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119646-B2 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20090258875-A1 | Fungicide Hydroximoyl-Tetrazole Derivatives | BAYER CROPSCIENCE AG (DE) | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258875-A1 | Fungicide Hydroximoyl-Tetrazole Derivatives | HAAO, CYP51A1, CYP8B1 | HTT 148/4885SMN1; SMN2 4458/4885EPHX1 1280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.