Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24713146 | 1.00 | ACE (0.40) | ACEMMECPA1ACE2CA1 | |
| SCHEMBL13337034 | 0.96 | ACE (0.38) | ACEMMECPA1ACE2CA1 | |
| SCHEMBL19502439 | 0.81 | DPP4 (0.46) | ACEMMECPA1ACE2CA1 | |
| SCHEMBL11949476 | 0.80 | MME (0.60) | ACEMMECPA1ACE2TSHR | |
| SCHEMBL20763967 | 0.79 | CA1 (0.48) | ACE2CA1CA2KMT2ADPP8 | |
| SCHEMBL24254004 | 0.77 | CA1 (0.43) | CA1CA2DPP4DPP8DPP9 | |
| SCHEMBL4780590 | 0.77 | DPP4 (0.33) | ACEMMECPA1ACE2CA1 | |
| SCHEMBL13876693 | 0.77 | ALDH1A1 (0.42) | CA1CA2CA7CA14HSD17B10 | |
| SCHEMBL7727537 | 0.77 | DPP4 (0.33) | ACEMMECPA1ACE2CA1 | |
| SCHEMBL10031629 | 0.77 | ALDH1A1 (0.42) | CA1CA2CA7CA14HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010141330-A1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-a]IMIDAZOLE-3-CARBOXYLIC ACID AMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-12-09 | — | — | WO | disclosed |