Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDK | P21741 | 4/20 | 0.56 |
| ▸ | FGF1 | P05230 | 1/20 | 0.53 |
| ▸ | FGF2 | P09038 | 1/20 | 0.53 |
| ▸ | VEGFA | P15692 | 1/20 | 0.53 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.51 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9898615 | 0.78 | MDK (0.65) | MDKFGF1FGF2VEGFAHPSE | |
| SCHEMBL9898618 | 0.78 | MDK (0.65) | MDKFGF1FGF2VEGFAHPSE | |
| SCHEMBL9898612 | 0.78 | MDK (0.65) | MDKFGF1FGF2VEGFAHPSE | |
| SCHEMBL15216220 | 0.78 | F2 (0.73) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL19751698 | 0.78 | F2 (0.73) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL4968230 | 0.78 | F2 (0.73) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL19017236 | 0.78 | F2 (0.73) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL24767163 | 0.76 | F2 (0.69) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL18549029 | 0.76 | F2 (0.69) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL22767679 | 0.76 | F2 (0.69) | F2PRSS1PRSS2PRSS3TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7858578-B2 | tissue engineering using a carbohydrate fucose-galactose attached to polyacrylamide or polyoxyethylene glycol; inducing neuronal outgrowth | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2010-12-28 | — | — | US | disclosed |