Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDK | P21741 | 4/20 | 0.65 |
| ▸ | FGF1 | P05230 | 1/20 | 0.64 |
| ▸ | FGF2 | P09038 | 1/20 | 0.64 |
| ▸ | VEGFA | P15692 | 1/20 | 0.64 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.49 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9898615 | 1.00 | MDK (0.65) | MDKFGF1FGF2VEGFAHPSE | |
| SCHEMBL9898612 | 1.00 | MDK (0.65) | MDKFGF1FGF2VEGFAHPSE | |
| SCHEMBL16264872 | 0.81 | MDK (0.75) | MDKFGF1FGF2VEGFAHPSE | |
| SCHEMBL18653674 | 0.81 | MDK (0.75) | MDKFGF1FGF2VEGFAHPSE | |
| SCHEMBL12975856 | 0.78 | MDK (0.56) | MDKFGF1FGF2VEGFAHPSE | |
| SCHEMBL19751698 | 0.78 | F2 (0.73) | PKMPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL19017236 | 0.78 | F2 (0.73) | PKMPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL4968230 | 0.78 | F2 (0.73) | PKMPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL15216220 | 0.78 | F2 (0.73) | PKMPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL8239820 | 0.77 | FGF1 (0.51) | MDKFGF1FGF2VEGFAHPSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9624255-B2 | Carbohydrate-mediated tumor targeting | ARIZONA BOARD OF REGENTS (US) | 2017-04-18 | — | — | US | claimed |
| US-20120148502-A1 | Carbohydrate-Mediated Tumor Targeting | Arizona Board of Regents, a body corporate of the State of Ariz. acting for and on behalf of Ariz. (US) | 2012-06-14 | — | — | US | claimed |
| US-9624255-B2 | Carbohydrate-mediated tumor targeting | ARIZONA BOARD OF REGENTS (US) | 2017-04-18 | — | — | US | disclosed |
| US-20120148502-A1 | Carbohydrate-Mediated Tumor Targeting | Arizona Board of Regents, a body corporate of the State of Ariz. acting for and on behalf of Ariz. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120148502-A1 | Carbohydrate-Mediated Tumor Targeting | CA14, CA13, CA12 | MDK 2783/4885FGF1 825/4885FGF2 498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.