Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HTR2A | P28223 | 3/20 | 0.52 |
| ▸ | HTR2B | P41595 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | NCF1 | P14598 | 1/20 | 0.51 |
| ▸ | CHKA | P35790 | 1/20 | 0.51 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | HRH2 | P25021 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12976188 | 0.91 | SMN1; SMN2 (0.47) | SMN1; SMN2HTR2AHTR2BCA2NCF1 | |
| SCHEMBL13460805 | 0.84 | SMN1; SMN2 (0.58) | SMN1; SMN2HTR2AHTR2BALDH1A1USP2 | |
| SCHEMBL25230821 | 0.81 | SMN1; SMN2 (0.52) | SMN1; SMN2HTR2AHTR2BCHKAALDH1A1 | |
| SCHEMBL32668994 | 0.81 | HTR2A (0.57) | SMN1; SMN2HTR2AHTR2BCHKAALDH1A1 | |
| Hydrochloric Acid SCHEMBL8804628 | 0.81 | HTR2A (0.60) | SMN1; SMN2HTR2AHTR2BCHKAALDH1A1 | |
| SCHEMBL8404672 | 0.81 | NAMPT (0.58) | ALDH1A1DRD2DRD3KCNH2MEN1 | |
| SCHEMBL24564964 | 0.78 | PRMT6 (0.69) | CA2NCF1CHKAPRMT6ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8804632 | 0.77 | SMN1; SMN2 (0.51) | SMN1; SMN2HTR2AHTR2BALDH1A1USP2 | |
| SCHEMBL10526530 | 0.76 | SMN1; SMN2 (0.74) | SMN1; SMN2HTR2AHTR2BMEN1KMT2A | |
| SCHEMBL8966405 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010140685-A1 | HETEROCYCLIC COMPOUND AND HEMATOPOIETIC STEM CELL AMPLIFIER | 日産化学工業株式会社 (JP) | 2010-12-09 | — | — | WO | disclosed |