Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12978167 | 0.90 | HTT (0.51) | HTTCYP3A4CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL12978156 | 0.87 | HTT (0.53) | HTTCYP3A4CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL12978149 | 0.87 | HTT (0.49) | HTTCYP3A4CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL12978152 | 0.86 | TRPV1 (0.48) | TRPV1OXTRKDM4E | |
| SCHEMBL12978145 | 0.82 | SMN1; SMN2 (0.59) | HTTCYP3A4CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL12977982 | 0.79 | HTT (0.61) | HTTCYP3A4CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL790954 | 0.79 | HTT (0.51) | HTTCYP3A4CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL790147 | 0.78 | HTT (0.61) | HTTCYP3A4CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL12977989 | 0.78 | HTT (0.60) | HTTCYP3A4CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL15093652 | 0.78 | HTT (0.47) | HTTCYP3A4CYP2C9CYP2B6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | BAYER CROPSCIENCE AG (DE) | 2010-12-02 | — | — | US | disclosed |
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | BAYER CROPSCIENCE AG (DE) | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | AAAS, DDT, QDPR | HTT 2101/4885CYP3A4 87/4885CYP2C9 310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.