Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 13/20 | 0.61 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | POLQ | O75417 | 1/20 | 0.52 |
| ▸ | VNN1 | O95497 | 1/20 | 0.49 |
| ▸ | MLYCD | O95822 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TEK | Q02763 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12977992 | 0.81 | TRPV1 (0.50) | GPBAR1TRPV1POLQMLYCDKDM4E | |
| SCHEMBL12978268 | 0.80 | GPBAR1 (0.59) | GPBAR1TRPV1POLQVNN1MLYCD | |
| SCHEMBL19245118 | 0.78 | GRIN2B (0.44) | GPBAR1TRPV1POLQVNN1MLYCD | |
| SCHEMBL12977968 | 0.78 | TRPV1 (0.55) | GPBAR1TRPV1POLQMLYCDHDAC8 | |
| SCHEMBL12978272 | 0.78 | TRPV1 (0.55) | GPBAR1TRPV1MLYCDKDM4EKMT2A | |
| SCHEMBL6237453 | 0.77 | KDM4E (0.68) | TRPV1MLYCDKDM4EKMT2A | |
| SCHEMBL13095766 | 0.77 | TRPV1 (0.56) | GPBAR1TRPV1MLYCDKDM4EKMT2A | |
| SCHEMBL12977961 | 0.77 | TRPV1 (0.60) | TRPV1POLQMLYCDKDM4EKMT2A | |
| SCHEMBL13095850 | 0.77 | TRPV1 (0.56) | TRPV1POLQMLYCDKDM4EKMT2A | |
| SCHEMBL12977958 | 0.77 | TRPV1 (0.54) | TRPV1POLQMLYCDKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | BAYER CROPSCIENCE AG (DE) | 2010-12-02 | — | — | US | disclosed |
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | BAYER CROPSCIENCE AG (DE) | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | AAAS, DDT, QDPR | GPBAR1 4037/4885TRPV1 2769/4885POLQ 1550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.