Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 15/20 | 0.58 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11448858 | 0.83 | CYP19A1 (0.58) | CYP19A1CYP11B2CYP11B1KCNH2 | |
| SCHEMBL11104201 | 0.72 | CYP19A1 (0.61) | CYP19A1CYP11B2CYP11B1KCNH2 | |
| SCHEMBL10974976 | 0.71 | CYP19A1 (0.60) | CYP19A1CYP11B2CYP11B1KCNH2 | |
| SCHEMBL10975948 | 0.71 | CYP19A1 (0.60) | CYP19A1CYP11B2CYP11B1KCNH2 | |
| Hydrochloric Acid SCHEMBL11065811 | 0.70 | CYP19A1 (0.58) | CYP19A1CYP11B2 | |
| Hydrochloric Acid SCHEMBL10973284 | 0.70 | CYP19A1 (0.58) | CYP19A1CYP11B2 | |
| SCHEMBL15729571 | 0.66 | ADRA1A (0.30) | — | |
| SCHEMBL24810573 | 0.65 | CYP19A1 (0.41) | CYP19A1CYP11B2CYP11B1KCNH2 | |
| SCHEMBL24810567 | 0.64 | CYP19A1 (0.40) | CYP19A1CYP11B2CYP11B1KCNH2 | |
| SCHEMBL8845131 | 0.64 | CYP19A1 (0.63) | CYP19A1CYP11B2CYP11B1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7846957-B2 | Aromatase inhibition to enhance assisted reproduction | ARES TRADING S.A. (CH) | 2010-12-07 | — | — | US | disclosed |
| US-7820706-B2 | Multiple dose aromatase inhibitor for treating infertility | ARES TRADING S.A. (CH) | 2010-10-26 | — | — | US | disclosed |