SCHEMBL129801

SCHEMBL129801

CCOC(=O)c1cccc(CC)c1

nearest known ligand 0.71

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.71
CYP4A11 Q02928 1/20 0.71
MEP1B Q16820 1/20 0.61
CA2 P00918 2/20 0.57
CA12 O43570 1/20 0.56
CA1 P00915 1/20 0.56
CA7 P43166 1/20 0.56
CA9 Q16790 1/20 0.56
CA14 Q9ULX7 1/20 0.56
NPC1 O15118 3/20 0.56
RAB9A P51151 3/20 0.56
MAPT P10636 2/20 0.56
SMN1; SMN2 Q16637 3/20 0.54
ALDH1A1 P00352 2/20 0.54
TSHR P16473 1/20 0.54
KMT2A Q03164 1/20 0.54
LOXL2 Q9Y4K0 1/20 0.53
KDM4E B2RXH2 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7473301 0.91 CYP4F2 (0.61) CYP4F2CYP4A11MEP1BCA2CA12
SCHEMBL2089661 0.89 CYP4F2 (0.68) CYP4F2CYP4A11MEP1BCA2CA12
SCHEMBL128387 0.89 CYP4F2 (0.72) CYP4F2CYP4A11MEP1BCA2CA12
SCHEMBL13291593 0.89 CYP4F2 (0.62) CYP4F2CYP4A11MEP1BMAPTSMN1; SMN2
SCHEMBL110276 0.88 CYP4F2 (0.65) CYP4F2CYP4A11CA2CA12CA1
SCHEMBL129800 0.88 CYP4F2 (0.66) CYP4F2CYP4A11MEP1BCA2CA12
SCHEMBL12035616 0.88 CYP4F2 (0.75) CYP4F2CYP4A11MEP1BCA2CA12
SCHEMBL4508966 0.88 CYP4F2 (0.66) CYP4F2CYP4A11MEP1BCA2CA12
SCHEMBL2450193 0.88 LOXL2 (0.71) CYP4F2CYP4A11MEP1BCA2CA12
SCHEMBL1198044 0.88 CYP4F2 (0.66) CYP4F2CYP4A11MEP1BCA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9620718-B2 Method for preparing a semiconducting layer CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2017-04-11 US claimed
US-20150188053-A1 METHOD FOR PREPARING A SEMICONDUCTING LAYER CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2015-07-02 US claimed
WO-2013190255-A9 METHOD FOR PREPARING A SEMICONDUCTING LAYER CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2015-01-08 WO claimed
WO-2013190255-A2 METHOD FOR PREPARING A SEMICONDUCTING LAYER CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2013-12-27 WO claimed
US-8569195-B2 Internal and external donor compounds for olefin polymerization catalysts II BASF CORPORATION (US) 2013-10-29 US claimed
US-20240024305-A1 METHODS AND COMPOSITIONS FOR TREATING RETINA-ASSOCIATED DISEASE USING CCR3-INHIBITORS ALKAHEST, INC. 2024-01-25 US disclosed
US-20240016775-A1 ANTI-CORONAVIRUS APPLICATION OF POLY ADP RIBOSE POLYMERASE INHIBITOR FUKANG (SHANGHAI) HEALTH TECHNOLOGY CO., LTD (CN) 2024-01-18 US disclosed
US-11711971-B2 Ink composition and method for manufacturing organic light emitting device LG CHEM, LTD. 2023-07-25 US disclosed
US-11711971-B2 Ink composition and method for manufacturing organic light emitting device LG CHEM, LTD. 2023-07-25 US disclosed
US-20230072658-A1 SMARCA DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2023-03-09 US disclosed
CN-114956933-A Marker containing isotope oxygen atom and preparation method and application thereof 清华大学 2022-08-30 CN disclosed
CN-111517902-B Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof 清华大学 2022-06-14 CN disclosed
EP-1534715-B1 FUROPYRIDINE AND FUROPYRIMIDINE DERIVATIVES FOR THE TREATMENT OF HYPER-PROLIFERATIVE DISORDERS BAYER PHARMACEUTICALS CORP (US) 2007-08-15 EP disclosed
US-20070173519-A1 Pyrazolopyrimidine derivatives or pharmaceutically acceptable salts thereof TEIJIN PHARMA LIMITED 2007-07-26 US disclosed
US-20070072898-A1 Pyrazolo[1,5-a]pyridine derivatives or pharmaceutically acceptable salts thereof TEIJIN PHARMA LIMITED 2007-03-29 US disclosed
EP-1651658-A1 NOVEL COMPOUNDS HAVING INHIBITORY ACTIVITY AGAINST SODIUM-DEPENDANT TRANSPORTER TANABE SEIYAKU CO., LTD. (JP) 2006-05-03 EP disclosed
WO-2005012326-A1 NOVEL COMPOUNDS HAVING INHIBITORY ACTIVITY AGAINST SODIUM-DEPENDANT TRANSPORTER TANABE SEIYAKU CO., LTD. (JP) 2005-02-10 WO disclosed
EP-0760359-B1 Method for preparing aromatic carbonate MITSUBISHI GAS CHEMICAL CO (JP) 1999-10-20 EP disclosed
US-5714627-A REACTING A DIALKYL CARBONATE WITH AN AROMATIC CARBOXYLIC ACID ARYL ESTER IN THE PRESENCE OF A CATALYST MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1998-02-03 US disclosed
EP-0760359-A1 Method for preparing aromatic carbonate MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1997-03-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070072898-A1 Pyrazolo[1,5-a]pyridine derivatives or pharmaceutically acceptable salts thereof MAPKAPK2, MAP4K2, MAPKAPK5 CYP4F2 3783/4885CYP4A11 3695/4885MEP1B 1645/4885
US-20070173519-A1 Pyrazolopyrimidine derivatives or pharmaceutically acceptable salts thereof MAPKAPK2, MAPKAPK5, MAPKAPK3 CYP4F2 2749/4885CYP4A11 4355/4885MEP1B 1149/4885
US-20240016775-A1 ANTI-CORONAVIRUS APPLICATION OF POLY ADP RIBOSE POLYMERASE INHIBITOR PARP3, PARP1, PARP4 CYP4F2 4732/4885CYP4A11 3137/4885MEP1B 348/4885
US-20240024305-A1 METHODS AND COMPOSITIONS FOR TREATING RETINA-ASSOCIATED DISEASE USING CCR3-INHIBITORS CCR3, CCR1, CCR4 CYP4F2 4794/4885CYP4A11 2858/4885MEP1B 4305/4885
US-20230072658-A1 SMARCA DEGRADERS AND USES THEREOF SMARCA1, SMARCB1, SMARCE1 CYP4F2 4684/4885CYP4A11 3925/4885MEP1B 591/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.