Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.72 |
| ▸ | FAAH | O00519 | 4/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | CNR1 | P21554 | 2/20 | 0.59 |
| ▸ | CNR2 | P34972 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | STS | P08842 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18328442 | 1.00 | EPHX2 (0.72) | EPHX2FAAHTRPV1HTTHPGD | |
| SCHEMBL14102773 | 1.00 | EPHX2 (0.72) | EPHX2FAAHTRPV1HTTHPGD | |
| SCHEMBL14102656 | 0.94 | EPHX2 (0.65) | EPHX2FAAHTRPV1HTTHPGD | |
| SCHEMBL15915089 | 0.94 | HPGD (0.67) | EPHX2FAAHHTTHPGDALDH1A1 | |
| SCHEMBL31412952 | 0.92 | FAAH (0.76) | EPHX2FAAHTRPV1CNR1CNR2 | |
| SCHEMBL17334875 | 0.92 | EPHX2 (0.62) | EPHX2FAAHTRPV1HTTHPGD | |
| SCHEMBL14102635 | 0.89 | EPHX2 (0.59) | EPHX2FAAHTRPV1HTTHPGD | |
| SCHEMBL3809498 | 0.89 | EPHX2 (0.84) | EPHX2FAAHTRPV1HPGDCNR1 | |
| SCHEMBL2092775 | 0.87 | CYP3A4 (0.61) | EPHX2HTTHPGDALDH1A1MAPT | |
| SCHEMBL27799721 | 0.85 | HPGD (0.57) | EPHX2FAAHHTTHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013130013-A1 | NOVEL COMPOUNDS AND USES THEREOF | NANYANG POLYTECHNIC (SG) | 2013-09-06 | — | — | WO | disclosed |
| WO-2010144055-A1 | NOVEL COMPOUNDS AND USES THEREOF | NANYANG POLYTECHNIC (SG) | 2010-12-16 | — | — | WO | disclosed |