⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13024045 | 0.68 | — | — | |
| SCHEMBL588597 | 0.68 | — | — | |
| SCHEMBL6021918 | 0.67 | — | — | |
| SCHEMBL10489061 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL22711054 | 0.67 | MMP2 (0.50) | — | |
| SCHEMBL7712387 | 0.67 | — | — | |
| SCHEMBL6665441 | 0.67 | MMP2 (0.50) | — | |
| SCHEMBL242033 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL28821640 | 0.63 | — | — | |
| Methane SCHEMBL1523810 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140235548-A1 | COMPOSITIONS AND METHODS FOR JAMM PROTEIN INHIBITION | CLEAVE BIOSCIENCES, INC. (US) | 2014-08-21 | — | — | US | claimed |
| EP-2710119-A1 | COMPOSITIONS AND METHODS FOR JAMM PROTEIN INHIBITION | Cleave Biosciences, Inc. (US) | 2014-03-26 | — | — | EP | claimed |
| WO-2012158435-A1 | COMPOSITIONS AND METHODS FOR JAMM PROTEIN INHIBITION | ZHOU HAN-JIE (US) | 2012-11-22 | — | — | WO | claimed |
| US-20120276152-A1 | SYSTEMS AND METHODS OF USING ZINC-CHELATOR TO TREAT MYOCARDIAL INFARCTION | ABBOTT CARDIOVASCULAR SYSTEMS INC., | 2012-11-01 | — | — | US | claimed |
| US-7576213-B2 | Vinylogous 4H-pyrones and their use in promoting plant growth | THE UNIVERSITY OF WESTERN AUSTRALIA (AU) | 2009-08-18 | — | — | US | claimed |
| US-20070105721-A1 | Vinylogous 4-Hpyrones and their use in promoting plant growth | THE UNIVERSITY OF WESTERN AUSTRALIA (AU) | 2007-05-10 | — | — | US | claimed |
| WO-2005061515-A1 | VINYLOGOUS 4H-PYRONES AND THEIR USE IN PROMOTING PLANT GROWTH | BOTANICAL GARDENS AND PARKS AUTHORITY (AU) | 2005-07-07 | — | — | WO | claimed |
| US-11021471-B2 | Antibacterial compounds | FORGE THERAPEUTICS, INC. (US) | 2021-06-01 | — | — | US | disclosed |
| US-11014871-B2 | “Multi-target” compounds with inhibitory activity towards histone deacetylases and tubulin polymerisation, for use in the treatment of cancer | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2021-05-25 | — | — | US | disclosed |
| US-10918106-B2 | Methods for hydraulic enhancement of crops | Sound Agriculture Company (US) | 2021-02-16 | — | — | US | disclosed |
| US-20200255413-A1 | ANTIBACTERIAL COMPOUNDS | BLACKSMITH MEDICINES, INC. | 2020-08-13 | — | — | US | disclosed |
| US-20200087648-A1 | PARKIN LIGASE ACTIVATION METHODS AND COMPOSITIONS | NYSNOBIO IRELAND DAC (IE) | 2020-03-19 | — | — | US | disclosed |
| EP-3621962-A2 | ANTIBACTERIAL COMPOUNDS | Forge Therapeutics, Inc. (US) | 2020-03-18 | — | — | EP | disclosed |
| US-20060199826-A1 | Cyclopropane compounds and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2006-09-07 | — | — | US | disclosed |
| EP-1694638-A1 | N-SUBSTITUTED-N-SULFONYLAMINOCYCLOPROPANE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | Japan Tobacco, Inc. (JP) | 2006-08-30 | — | — | EP | disclosed |
| EP-1694410-A2 | CYCLOPROPANE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | Japan Tobacco, Inc. (JP) | 2006-08-30 | — | — | EP | disclosed |
| US-20050222146-A1 | N-substituted-n-sulfonylaminocyclopropane compounds and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2005-10-06 | — | — | US | disclosed |
| WO-2005061515-A1 | VINYLOGOUS 4H-PYRONES AND THEIR USE IN PROMOTING PLANT GROWTH | BOTANICAL GARDENS AND PARKS AUTHORITY (AU) | 2005-07-07 | — | — | WO | disclosed |
| WO-2005058808-A1 | N-SUBSTITUTED-N-SULFONYLAMINOCYCLOPROPANE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2005-06-30 | — | — | WO | disclosed |
| WO-2005058884-A2 | CYCLOPROPANE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2005-06-30 | — | — | WO | disclosed |