SCHEMBL1298504

SCHEMBL1298504

c1ccc(C2COC(c3cccc(C4=NC(c5ccccc5)CO4)c3)=N2)cc1

nearest known ligand 0.70

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.70
RAB9A P51151 2/20 0.70
ALDH1A1 P00352 3/20 0.61
MAPT P10636 2/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
TAAR1 Q96RJ0 5/20 0.54
POLB P06746 1/20 0.46
HTT P42858 2/20 0.45
LMNA P02545 1/20 0.45
MEN1 O00255 1/20 0.44
TSHR P16473 1/20 0.44
KMT2A Q03164 1/20 0.44
HSD17B10 Q99714 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14352146 1.00 NPC1 (0.70) NPC1RAB9AALDH1A1MAPTSMN1; SMN2
SCHEMBL13495018 0.91 NPC1 (0.71) NPC1RAB9AALDH1A1MAPTSMN1; SMN2
SCHEMBL1149438 0.91 NPC1 (0.71) NPC1RAB9AALDH1A1MAPTSMN1; SMN2
SCHEMBL29938562 0.91 NPC1 (0.71) NPC1RAB9AALDH1A1MAPTSMN1; SMN2
SCHEMBL9614459 0.89 NPC1 (0.61) NPC1RAB9AALDH1A1MAPTSMN1; SMN2
SCHEMBL8304084 0.89 NPC1 (0.62) NPC1RAB9AALDH1A1MAPTSMN1; SMN2
SCHEMBL8550159 0.89 NPC1 (0.62) NPC1RAB9AALDH1A1MAPTSMN1; SMN2
SCHEMBL8304089 0.89 NPC1 (0.62) NPC1RAB9AALDH1A1MAPTSMN1; SMN2
SCHEMBL8307476 0.89 NPC1 (0.62) NPC1RAB9AALDH1A1MAPTSMN1; SMN2
SCHEMBL8304092 0.89 NPC1 (0.62) NPC1RAB9AALDH1A1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5091259-A Flame retardant, flexible POLYPLASTICS CO., LTD. (JP) 1992-02-25 US claimed
US-4987167-A Flexible dielectric coverings POLYPLASTICS CO., LTD. (JP) 1991-01-22 US claimed
EP-2660295-B1 Metal article coated with a composition comprising olefinic double bonds EVONIK OPERATIONS GMBH (DE) 2022-06-08 EP disclosed
EP-2783835-B1 METHOD FOR MANUFACTURING A TUBE CLAD WITH AN INNER LINER EVONIK DEGUSSA GMBH (DE) 2019-09-11 EP disclosed
US-10113671-B2 Process for the production of a pipe lined with an inliner EVONIK DEGUSSA GMBH (DE) 2018-10-30 US disclosed
US-9556358-B2 Coated metallic article EVONIK DEGUSSA GMBH (DE) 2017-01-31 US disclosed
US-20140291032-A1 PROCESS FOR THE PRODUCTION OF A PIPE LINED WITH AN INLINER EVONIK INDUSTRIES AG (DE) 2014-10-02 US disclosed
EP-2783835-A1 Method for manufacturing a tube clad with an inner liner Evonik Industries AG (DE) 2014-10-01 EP disclosed
EP-2660295-A1 Metal article coated with a composition comprising olefinic double bonds Evonik Industries AG (DE) 2013-11-06 EP disclosed
US-20130287981-A1 COATED METALLIC ARTICLE EVONIK INDUSTRIES AG (DE) 2013-10-31 US disclosed
US-8545981-B2 Artificial hair made of flame-retardant polyester KANEKA CORPORATION (JP) 2013-10-01 US disclosed
US-5049603-A Polyester resin composition and molded articles thereof POLYPLASTICS CO., LTD. (JP) 1991-09-17 US disclosed
US-5039760-A With bisoxazoline to improve heat resistant flexibility and strength POLYPLASTICS CO., LTD. (JP) 1991-08-13 US disclosed
US-4987167-A Flexible dielectric coverings POLYPLASTICS CO., LTD. (JP) 1991-01-22 US disclosed
EP-0406010-A1 Polyester resin composition POLYPLASTICS CO. LTD. (JP) 1991-01-02 EP disclosed
EP-0400936-A1 Flame-retardant polyester resin compositions POLYPLASTICS CO. LTD. (JP) 1990-12-05 EP disclosed
US-4954541-A POLYESTER, HALOGENATED COMPOUND, HETEROCYCLIC COMPOUND POLYPLASTICS CO., LTD. (JP) 1990-09-04 US disclosed
EP-0382487-A2 Polyester resin composition POLYPLASTICS CO. LTD. (JP) 1990-08-16 EP disclosed
EP-0320159-A1 Flame-retardant resin composition and electric wire POLYPLASTICS CO. LTD. (JP) 1989-06-14 EP disclosed
US-4806588-A BLEND OF PET, POLYETHERS, BLOCK POLYMERS, IONOMERS, OXAZOLINE COMPOUNDS, POLYESTER ELASTOMERS, GLASS FIBERS TOYO BOSEKI KABUSHIKI KAISHA (JP) 1989-02-21 US disclosed