SCHEMBL12986980

SCHEMBL12986980

CC(C)N(CCC(c1ccccc1)c1cc(COC(=O)/C=C/C(=O)OCc2ccc(OCc3ccccc3)c(C(CCN(C(C)C)C(C)C)c3ccccc3)c2)ccc1OCc1ccccc1)C(C)C

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 3/20 0.59
CHRM1 P11229 3/20 0.59
HCAR2 Q8TDS4 4/20 0.43
CHRM3 P20309 3/20 0.43
LMNA P02545 3/20 0.43
CHRM5 P08912 2/20 0.43
HRH1 P35367 2/20 0.43
ESR1 P03372 1/20 0.43
CHRM4 P08173 1/20 0.43
MAPT P10636 1/20 0.43
KCNE1 P15382 1/20 0.43
PTGS1 P23219 1/20 0.43
HRH2 P25021 1/20 0.43
HTR2A P28223 1/20 0.43
SLC6A4 P31645 1/20 0.43
ADRA1A P35348 1/20 0.43
OPRK1 P41145 1/20 0.43
KCNQ1 P51787 1/20 0.43
KCNH2 Q12809 1/20 0.43
CACNA1C Q13936 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14696913 0.97 CHRM2 (0.56) CHRM2CHRM1HCAR2CHRM3LMNA
SCHEMBL14696914 0.97 CHRM2 (0.56) CHRM2CHRM1HCAR2CHRM3LMNA
SCHEMBL8431055 0.91 CHRM2 (0.62) CHRM2CHRM1CHRM3LMNACHRM5
SCHEMBL2167225 0.90 CHRM2 (0.67) CHRM2CHRM1CHRM3LMNACHRM5
SCHEMBL2166567 0.88 CHRM2 (0.59) CHRM2CHRM1CHRM3LMNACHRM5
SCHEMBL28350442 0.87 CHRM2 (0.75) CHRM2CHRM1HCAR2CHRM3LMNA
Fumaric Acid SCHEMBL12986978 0.86 CHRM2 (0.67) CHRM2CHRM1CHRM3LMNACHRM5
Fumaric Acid SCHEMBL14696915 0.86 CHRM2 (0.67) CHRM2CHRM1CHRM3LMNACHRM5
SCHEMBL814972 0.86 CHRM2 (0.72) CHRM2CHRM1HCAR2CHRM3LMNA
SCHEMBL14709881 0.86 CHRM2 (0.72) CHRM2CHRM1HCAR2CHRM3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9085509-B2 Process for preparing fesoterodine ALEMBIC PHARMACEUTICALS LIMITED (IN) 2015-07-21 US disclosed
EP-2686288-B1 A PROCESS FOR PREPARING FESOTERODINE ALEMBIC PHARMACEUTICALS LTD (IN) 2015-03-25 EP disclosed
US-20140039216-A1 PROCESS FOR PREPARING FESOTERODINE ALEMBIC PHARMACEUTICALS LIMITED (IN) 2014-02-06 US disclosed
EP-2686288-A1 A PROCESS FOR PREPARING FESOTERODINE Alembic Pharmaceuticals Limited (IN) 2014-01-22 EP disclosed
WO-2012137047-A1 A PROCESS FOR PREPARING FESOTERODINE ALEMBIC PHARMACEUTICALS LIMITED (IN) 2012-10-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140039216-A1 PROCESS FOR PREPARING FESOTERODINE FES, QDPR, CYP4F3 CHRM2 417/4885CHRM1 940/4885HCAR2 3557/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.