Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 12/20 | 0.52 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12989367 | 0.83 | LPAR1 (0.72) | LPAR1LPAR3MEN1KMT2A | |
| SCHEMBL12988949 | 0.83 | LPAR1 (0.72) | LPAR1LPAR3MEN1KMT2A | |
| SCHEMBL12989650 | 0.76 | LPAR1 (0.77) | LPAR1LPAR3 | |
| SCHEMBL12989052 | 0.73 | LPAR1 (0.73) | LPAR1LPAR3MEN1KMT2A | |
| SCHEMBL14710744 | 0.72 | SMN1; SMN2 (0.53) | LPAR1MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL23917462 | 0.72 | LPAR1 (0.57) | LPAR1LPAR3MEN1KMT2A | |
| SCHEMBL23087216 | 0.71 | MEN1 (0.66) | MEN1KMT2AHTTCYP1A2CYP2C19 | |
| SCHEMBL12988950 | 0.71 | ROCK2 (0.46) | LPAR1MEN1KMT2AHTTLMNA | |
| SCHEMBL16477201 | 0.70 | LPAR1 (0.74) | LPAR1LPAR3CYP2C19 | |
| SCHEMBL13195363 | 0.70 | LPAR1 (0.87) | LPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012138648-A1 | COMPOSITIONS AND METHODS FOR MODULATING LPA RECEPTORS | IRM LLC (BM) | 2012-10-11 | — | — | WO | disclosed |