Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16058329 | 0.90 | ERN1 (0.64) | ERN1 | |
| SCHEMBL26082860 | 0.89 | ERN1 (0.47) | ERN1 | |
| SCHEMBL16058511 | 0.88 | ERN1 (0.51) | ERN1 | |
| SCHEMBL17509381 | 0.88 | ERN1 (0.44) | ERN1 | |
| SCHEMBL5337591 | 0.84 | MCL1 (0.60) | ERN1 | |
| SCHEMBL30462312 | 0.83 | ERN1 (0.55) | ERN1 | |
| SCHEMBL17509379 | 0.82 | ERN1 (0.46) | ERN1 | |
| SCHEMBL19592051 | 0.82 | ERN1 (0.40) | ERN1 | |
| SCHEMBL31017149 | 0.81 | ERN1 (0.53) | ERN1 | |
| SCHEMBL16063778 | 0.80 | ERN1 (0.40) | ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9085511-B2 | Atropisomeric 1,8-bisphenolnapthalenes and their use in enantioselective recognition and asymmetric synthesis | GEORGETOWN UNIVERSITY (US) | 2015-07-21 | — | — | US | disclosed |
| US-9085511-B2 | Atropisomeric 1,8-bisphenolnapthalenes and their use in enantioselective recognition and asymmetric synthesis | GEORGETOWN UNIVERSITY (US) | 2015-07-21 | — | — | US | disclosed |
| US-9085511-B2 | Atropisomeric 1,8-bisphenolnapthalenes and their use in enantioselective recognition and asymmetric synthesis | GEORGETOWN UNIVERSITY (US) | 2015-07-21 | — | — | US | disclosed |
| US-20140128637-A1 | ATROPISOMERIC 1,8-BISPHENOLNAPTHALENES AND THEIR USE IN ENANTIOSELECTIVE RECOGNITION AND ASYMMETRIC SYNTHESIS | NATIONAL SCIENCE FOUNDATION | 2014-05-08 | — | — | US | disclosed |
| US-20140128637-A1 | ATROPISOMERIC 1,8-BISPHENOLNAPTHALENES AND THEIR USE IN ENANTIOSELECTIVE RECOGNITION AND ASYMMETRIC SYNTHESIS | NATIONAL SCIENCE FOUNDATION | 2014-05-08 | — | — | US | disclosed |
| US-20140128637-A1 | ATROPISOMERIC 1,8-BISPHENOLNAPTHALENES AND THEIR USE IN ENANTIOSELECTIVE RECOGNITION AND ASYMMETRIC SYNTHESIS | NATIONAL SCIENCE FOUNDATION | 2014-05-08 | — | — | US | disclosed |
| WO-2012138654-A2 | ATROPISOMERIC 1,8-BISPHENOLNAPTHALENES AND THEIR USE IN ENANTIOSELECTIVE RECOGNITION AND ASYMMETRIC SYNTHESIS | GEORGETOWN UNIVERSITY (US) | 2012-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140128637-A1 | ATROPISOMERIC 1,8-BISPHENOLNAPTHALENES AND THEIR USE IN ENANTIOSELECTIVE RECOGNITION AND ASYMMETRIC SYNTHESIS | CYP2A7, CYP4A11, CYP2C8 | ERN1 3492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.