Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 19/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12989293 | 0.90 | ERN1 (0.53) | ERN1 | |
| SCHEMBL26082860 | 0.83 | ERN1 (0.47) | ERN1 | |
| SCHEMBL17509381 | 0.82 | ERN1 (0.44) | ERN1 | |
| SCHEMBL4734113 | 0.79 | ERN1 (1.00) | ERN1 | |
| SCHEMBL16058511 | 0.79 | ERN1 (0.51) | ERN1 | |
| SCHEMBL5337591 | 0.76 | MCL1 (0.60) | ERN1 | |
| SCHEMBL26259714 | 0.75 | ALDH1A1 (0.53) | KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL30462312 | 0.75 | ERN1 (0.55) | ERN1 | |
| SCHEMBL17509379 | 0.73 | ERN1 (0.46) | ERN1 | |
| SCHEMBL19592051 | 0.73 | ERN1 (0.40) | ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014144197-A1 | STEREODYNAMIC CHEMOSENSORS | GEORGETOWN UNIVERSITY (US) | 2014-09-18 | — | — | WO | disclosed |