Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | CFTR | P13569 | 2/20 | 0.43 |
| ▸ | GOPC | Q9HD26 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11871868 | 0.83 | HSD17B10 (0.40) | MAPTTSHRHSD17B10SLC6A2SLC6A4 | |
| SCHEMBL14392243 | 0.83 | SLC6A4 (0.43) | MAPTTSHRHSD17B10SLC6A2SLC6A4 | |
| SCHEMBL8793977 | 0.80 | KCNN4 (0.50) | MAPTTSHRHSD17B10SLC6A2SLC6A4 | |
| SCHEMBL24016014 | 0.80 | POLB (0.53) | MAPTTSHRHSD17B10SMN1; SMN2CYP19A1 | |
| SCHEMBL31407193 | 0.78 | CYP3A4 (0.52) | MAPTTSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10063384 | 0.77 | IDO1 (0.44) | TSHRHSD17B10GAA | |
| SCHEMBL25591483 | 0.76 | NPC1 (0.43) | MAPTTSHRHSD17B10SMN1; SMN2CYP19A1 | |
| SCHEMBL31036989 | 0.76 | NPC1 (0.49) | MAPTTSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL2482817 | 0.74 | SLC6A4 (0.48) | MAPTTSHRHSD17B10SLC6A2SLC6A4 | |
| SCHEMBL8795521 | 0.73 | SMN1; SMN2 (0.53) | MAPTTSHRHSD17B10SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2261218-A2 | Process for preparing phenyl-, pyridinyl- or pyrimidinyl-substituted imidazoles | Eisai R&D Management Co., Ltd. (JP) | 2010-12-15 | — | — | EP | disclosed |
| EP-1757591-A1 | CINNAMIDE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2007-02-28 | — | — | EP | disclosed |