Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.46 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | F9 | P00740 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL990514 | 1.00 | GAA (0.48) | GAAL3MBTL1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL10169783 | 1.00 | GAA (0.48) | GAAL3MBTL1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL10137639 | 1.00 | GAA (0.48) | GAAL3MBTL1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL13137377 | 1.00 | GAA (0.48) | GAAL3MBTL1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL27857174 | 1.00 | GAA (0.48) | GAAL3MBTL1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6872366 | 1.00 | GAA (0.48) | GAAL3MBTL1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL990512 | 1.00 | GAA (0.48) | GAAL3MBTL1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL14341272 | 0.97 | ALDH1A1 (0.47) | GAAL3MBTL1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL14341281 | 0.97 | ALDH1A1 (0.47) | GAAL3MBTL1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL21104774 | 0.97 | ALDH1A1 (0.47) | GAAL3MBTL1ALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7858737-B2 | Heterogeneous foldamers containing α, β, and/or γ-amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-12-28 | — | — | US | disclosed |