Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 4/20 | 0.51 |
| ▸ | HTR2B | P41595 | 3/20 | 0.51 |
| ▸ | SCD | O00767 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3723794 | 0.87 | OPRM1 (0.65) | OPRM1OPRD1OPRK1OPRL1HTR2C | |
| SCHEMBL2675996 | 0.84 | OPRM1 (0.62) | OPRM1OPRD1OPRK1OPRL1HTR2C | |
| SCHEMBL4934890 | 0.82 | HTR2C (0.58) | OPRM1OPRD1OPRK1OPRL1HTR2C | |
| SCHEMBL2675232 | 0.81 | OPRM1 (0.52) | OPRM1OPRD1OPRK1OPRL1HTR2C | |
| SCHEMBL5871239 | 0.80 | OPRM1 (0.54) | OPRM1OPRD1OPRK1OPRL1HTR2C | |
| SCHEMBL2709111 | 0.79 | HTR2C (0.77) | OPRM1OPRD1OPRK1OPRL1HTR2C | |
| SCHEMBL14349454 | 0.79 | OPRM1 (0.53) | OPRM1OPRD1OPRK1OPRL1HTR2C | |
| Hydrochloric Acid SCHEMBL3947175 | 0.78 | HTR2C (0.75) | OPRM1OPRD1OPRK1OPRL1HTR2C | |
| SCHEMBL14282272 | 0.78 | OPRM1 (0.52) | OPRM1OPRD1OPRK1OPRL1HTR2C | |
| SCHEMBL29016956 | 0.77 | HTR2C (0.55) | OPRM1OPRD1OPRK1OPRL1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2261218-A2 | Process for preparing phenyl-, pyridinyl- or pyrimidinyl-substituted imidazoles | Eisai R&D Management Co., Ltd. (JP) | 2010-12-15 | — | — | EP | disclosed |