Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 7/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL907640 | 0.84 | AOC3 (0.70) | AOC3LMNAHTR2AHRH1SLC6A2 | |
| SCHEMBL907809 | 0.84 | AOC3 (0.70) | AOC3LMNAHTR2AHRH1SLC6A2 | |
| SCHEMBL804251 | 0.84 | AOC3 (0.70) | AOC3LMNAHTR2AHRH1SLC6A2 | |
| SCHEMBL22807616 | 0.84 | AOC3 (0.63) | AOC3LMNAHTR2AHRH1SLC6A2 | |
| Hydrochloric Acid SCHEMBL7244349 | 0.83 | AOC3 (0.68) | AOC3LMNAHTR2AHRH1SLC6A2 | |
| SCHEMBL6284970 | 0.83 | AOC3 (0.68) | AOC3LMNAHTR2AHRH1SLC6A2 | |
| SCHEMBL10430789 | 0.82 | AOC3 (0.61) | AOC3LMNAHTR2AHRH1SLC6A2 | |
| SCHEMBL6744933 | 0.81 | AOC3 (1.00) | AOC3LMNA | |
| SCHEMBL9729386 | 0.79 | AOC3 (0.63) | AOC3LMNAHTR2AHRH1SLC6A2 | |
| SCHEMBL10297493 | 0.79 | AOC3 (0.63) | AOC3LMNAHTR2AHRH1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2261218-A2 | Process for preparing phenyl-, pyridinyl- or pyrimidinyl-substituted imidazoles | Eisai R&D Management Co., Ltd. (JP) | 2010-12-15 | — | — | EP | disclosed |