SCHEMBL6744933

SCHEMBL6744933

CN(N)CC(O)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 19/20 1.00
LMNA P02545 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Maleic Acid SCHEMBL27594752 0.88 AOC3 (0.77) AOC3LMNA
SCHEMBL907640 0.83 AOC3 (0.70) AOC3LMNA
SCHEMBL907809 0.83 AOC3 (0.70) AOC3LMNA
SCHEMBL804251 0.83 AOC3 (0.70) AOC3LMNA
Hydrochloric Acid SCHEMBL7244349 0.81 AOC3 (0.68) AOC3LMNA
SCHEMBL6284970 0.81 AOC3 (0.68) AOC3LMNA
SCHEMBL12993183 0.81 AOC3 (0.68) AOC3LMNA
SCHEMBL22807616 0.78 AOC3 (0.63) AOC3LMNA
SCHEMBL10297493 0.78 AOC3 (0.63) AOC3LMNA
SCHEMBL9729386 0.78 AOC3 (0.63) AOC3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040106654-A1 Inhibitors of copper-containing amine oxidases SMITH DAVID JOHN (FI) 2004-06-03 US claimed
EP-1313718-A2 INHIBITORS OF COPPER-CONTAINING AMINE OXIDASES Biotie Therapies Corp. (FI) 2003-05-28 EP claimed
US-20020173521-A1 Inhibitors of copper-containing amine oxidases BIOTIE THERAPIES CORP. 2002-11-21 US claimed
WO-2002002090-A2 INHIBITORS OF COPPER-CONTAINING AMINE OXIDASES BIOTIE THERAPIES CORP. (FI) 2002-01-10 WO claimed
US-20040106654-A1 Inhibitors of copper-containing amine oxidases SMITH DAVID JOHN (FI) 2004-06-03 US disclosed
US-6624202-B2 Antiinflammatory agents; antiarthritic agents; skin disorders BIOTIE THERAPIES CORP. (FI) 2003-09-23 US disclosed
EP-1301495-A2 INHIBITORS OF COPPER-CONTAINING AMINE OXIDASES Biotie Therapies Corp. (FI) 2003-04-16 EP disclosed
EP-1301526-A1 OXIDATION PROCESS FOR PREPARING THE INTERMEDIATE 6.ALPHA.,9.ALPHA.-DIFLUORO-11.BETA.,17.ALPHA.-DIHYDROXY-16.ALPHA.-METHYL-ANDROST-1,4-DIEN-3-ONE 17.BETA.-CARBOXYLIC ACID GLAXO GROUP LIMITED (GB) 2003-04-16 EP disclosed
US-20020173521-A1 Inhibitors of copper-containing amine oxidases BIOTIE THERAPIES CORP. 2002-11-21 US disclosed
WO-2002008243-A1 OXIDATION PROCESS FOR PREPARING THE INTERMEDIATE 6.ALPHA.,9.ALPHA.-DIFLUORO-11.BETA.,17.ALPHA.-DIHYDROXY-16.ALPHA.-METHYL-ANDROST-1,4-DIEN-3-ONE 17.BETA.-CARBOXYLIC ACID GLAXO GROUP LIMITED (GB) 2002-01-31 WO disclosed
WO-2002002541-A2 INHIBITORS OF COPPER-CONTAINING AMINE OXIDASES BIOTIE THERAPIES CORP. (FI) 2002-01-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040106654-A1 Inhibitors of copper-containing amine oxidases VCAM1, AOC3, AOC2 AOC3 2/4885LMNA 4636/4885
US-20020173521-A1 Inhibitors of copper-containing amine oxidases VCAM1, AOC3, AOC2 AOC3 2/4885LMNA 4636/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.