Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.31 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12822354 | 0.92 | — | — | |
| SCHEMBL12823711 | 0.92 | — | — | |
| SCHEMBL12719057 | 0.88 | KCNA3 (0.31) | KCNA3NFE2L2 | |
| SCHEMBL13586299 | 0.87 | — | — | |
| SCHEMBL12719051 | 0.87 | KCNA3 (0.32) | PDE4APDE4BPDE4CPDE4DKCNA3 | |
| SCHEMBL10302939 | 0.83 | PTGS1 (0.35) | KCNA3NFE2L2 | |
| SCHEMBL13586534 | 0.83 | APP (0.32) | — | |
| SCHEMBL12907234 | 0.82 | NFE2L2 (0.33) | KCNA3NFE2L2 | |
| SCHEMBL12906983 | 0.81 | NFE2L2 (0.38) | NFE2L2 | |
| SCHEMBL10302927 | 0.81 | TUBB1 (0.35) | PDE4APDE4BPDE4CPDE4DKCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2266941-A1 | TRICYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | Chisso Corporation (JP) | 2010-12-29 | — | — | EP | disclosed |