Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.37 |
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PFKFB2 | O60825 | 4/20 | 0.35 |
| ▸ | PFKFB1 | P16118 | 4/20 | 0.35 |
| ▸ | PFKFB3 | Q16875 | 4/20 | 0.35 |
| ▸ | NSD2 | O96028 | 2/20 | 0.34 |
| ▸ | AS3MT | Q9HBK9 | 2/20 | 0.34 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.34 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12995505 | 0.95 | HRH3 (0.36) | HRH3TBK1JAK2PFKFB2PFKFB1 | |
| SCHEMBL2886552 | 0.94 | HRH3 (0.37) | HRH3TBK1JAK2NPC1CYP1A2 | |
| SCHEMBL12995897 | 0.92 | NPC1 (0.34) | HRH3NPC1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL13198217 | 0.91 | HRH3 (0.36) | HRH3TBK1JAK2NPC1CYP1A2 | |
| SCHEMBL12995501 | 0.90 | HRH3 (0.33) | HRH3TBK1JAK2PFKFB2PFKFB1 | |
| SCHEMBL10096713 | 0.89 | S1PR3 (0.36) | HRH3NPC1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL12995115 | 0.89 | HRH3 (0.36) | HRH3TBK1JAK2DYRK1AACACB | |
| SCHEMBL12994593 | 0.89 | HRH3 (0.36) | HRH3TBK1JAK2DYRK1AACACB | |
| SCHEMBL12995602 | 0.89 | S1PR3 (0.36) | HRH3NPC1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL13198938 | 0.89 | HRH3 (0.36) | HRH3TBK1JAK2DYRK1AACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305100-A1 | METHODS FOR TREATING HEPATITIS C | PTC THERAPEUTICS, INC. (US) | 2010-12-02 | — | — | US | disclosed |
| US-7772271-B2 | Methods for treating hepatitis C | PTC THERAPEUTICS, INC. (US) | 2010-08-10 | — | — | US | disclosed |
| US-7772271-B2 | Methods for treating hepatitis C | PTC THERAPEUTICS, INC. (US) | 2010-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305100-A1 | METHODS FOR TREATING HEPATITIS C | HAVCR2, EIF2AK2, MAVS | HRH3 3336/4885TBK1 1215/4885JAK2 275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.