Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.64 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.64 |
| ▸ | RELA | Q04206 | 2/20 | 0.64 |
| ▸ | CASP3 | P42574 | 5/20 | 0.63 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.63 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | THRB | P10828 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 9/20 | 0.56 |
| ▸ | RAB9A | P51151 | 9/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1734841 | 0.84 | NPC1 (0.76) | KDM4EALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL29622897 | 0.84 | NPC1 (0.76) | KDM4EALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL5834587 | 0.84 | LMNA (0.59) | KDM4EALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL23748392 | 0.83 | NPC1 (0.73) | KDM4EALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL2250992 | 0.81 | SMN1; SMN2 (0.70) | KDM4EALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL30153407 | 0.81 | SMN1; SMN2 (0.70) | KDM4EALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL1065877 | 0.80 | NPC1 (0.68) | KDM4EALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL1734922 | 0.79 | KDM4E (0.61) | KDM4EALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL24881921 | 0.79 | SMN1; SMN2 (0.72) | KDM4EALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL2688302 | 0.79 | SMN1; SMN2 (0.53) | KDM4EALDH1A1SMN1; SMN2LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010137349-A1 | AGENT FOR TREATMENT OR PREVENTION OF DISEASES ASSOCIATED WITH ACTIVITY OF NEUROTROPHIC FACTORS | 住友化学株式会社 (JP) | 2010-12-02 | — | — | WO | disclosed |