Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.42 |
| ▸ | P2RY2 | P41231 | 17/20 | 0.41 |
| ▸ | P2RY6 | Q15077 | 9/20 | 0.41 |
| ▸ | P2RY4 | P51582 | 8/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13002370 | 1.00 | FBP1 (0.43) | FBP1P2RY14P2RY2P2RY6P2RY4 | |
| SCHEMBL24833618 | 0.87 | FBP1 (0.55) | FBP1P2RY14P2RY2P2RY6P2RY4 | |
| SCHEMBL14599960 | 0.87 | P2RY14 (0.38) | FBP1P2RY14P2RY2P2RY6P2RY4 | |
| SCHEMBL13259502 | 0.85 | FBP1 (0.53) | FBP1P2RY2P2RY6P2RY4 | |
| SCHEMBL26074117 | 0.85 | FBP1 (0.53) | FBP1P2RY2P2RY6P2RY4 | |
| SCHEMBL14985142 | 0.85 | FBP1 (0.53) | FBP1P2RY2P2RY6P2RY4 | |
| SCHEMBL14619450 | 0.83 | P2RY2 (0.53) | FBP1P2RY14P2RY2P2RY6P2RY4 | |
| SCHEMBL14985143 | 0.82 | FBP1 (0.56) | FBP1P2RY14P2RY2P2RY6P2RY4 | |
| SCHEMBL23657026 | 0.82 | FBP1 (0.56) | FBP1P2RY14P2RY2P2RY6P2RY4 | |
| SCHEMBL10014684 | 0.80 | FBP1 (0.50) | FBP1P2RY14P2RY2P2RY6P2RY4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851456-B2 | P2Y6 receptor agonists for treating lung diseases | INSPIRE PHARMACEUTICALS, INC. (US) | 2010-12-14 | — | — | US | disclosed |