Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 12/20 | 0.46 |
| ▸ | CALCA | P06881 | 7/20 | 0.44 |
| ▸ | MC5R | P33032 | 1/20 | 0.41 |
| ▸ | MC3R | P41968 | 1/20 | 0.41 |
| ▸ | MC1R | Q01726 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | UGCG | Q16739 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12713330 | 0.91 | MC4R (0.46) | MC4RCALCAMC5RMC3RMC1R | |
| SCHEMBL12713328 | 0.91 | MC4R (0.46) | MC4RCALCAMC5RMC3RMC1R | |
| SCHEMBL12713202 | 0.85 | CALCA (0.48) | MC4RCALCAMC5RMC3RMC1R | |
| SCHEMBL12713338 | 0.85 | CALCA (0.43) | MC4RCALCAMC5RMC3RMC1R | |
| SCHEMBL12713332 | 0.85 | CALCA (0.43) | MC4RCALCAMC5RMC3RMC1R | |
| SCHEMBL12713336 | 0.85 | CALCA (0.43) | MC4RCALCAMC5RMC3RMC1R | |
| SCHEMBL12713335 | 0.85 | CALCA (0.43) | MC4RCALCAMC5RMC3RMC1R | |
| SCHEMBL13002978 | 0.83 | CALCA (0.45) | MC4RCALCAMC5RMC3RMC1R | |
| SCHEMBL12713320 | 0.82 | CALCA (0.45) | MC4RCALCAMC5RMC3RMC1R | |
| SCHEMBL12713321 | 0.82 | CALCA (0.45) | MC4RCALCAMC5RMC3RMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004604-B1 | SUBSTITUTED PHENYLPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS | SANTHERA PHARMACEUTICALS CH (CH) | 2010-12-01 | — | — | EP | disclosed |