Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | MC5R | P33032 | 1/20 | 0.38 |
| ▸ | MC3R | P41968 | 1/20 | 0.38 |
| ▸ | MC1R | Q01726 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.37 |
| ▸ | CALCA | P06881 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12713046 | 0.90 | MC4R (0.47) | MEN1KMT2AHTR1AHTR7EPHX2 | |
| SCHEMBL12713076 | 0.84 | CALCA (0.46) | EPHX2MC4RMC5RMC3RMC1R | |
| SCHEMBL12713057 | 0.83 | MC4R (0.44) | MEN1KMT2AHTR1AHTR7MC4R | |
| SCHEMBL12713299 | 0.83 | MEN1 (0.40) | MEN1KMT2AHTR1AHTR7EPHX2 | |
| SCHEMBL12713085 | 0.82 | CALCA (0.46) | EPHX2MC4RMC5RMC3RMC1R | |
| SCHEMBL12713297 | 0.81 | HDAC8 (0.51) | MEN1KMT2AHTR1AHTR7EPHX2 | |
| SCHEMBL12738097 | 0.81 | MC4R (0.55) | MEN1KMT2AHTR1AHTR7MC4R | |
| SCHEMBL12713097 | 0.81 | CALCA (0.43) | EPHX2MC4RMC5RMC3RMC1R | |
| SCHEMBL12713089 | 0.80 | CALCA (0.45) | EPHX2MC4RMC5RMC3RMC1R | |
| SCHEMBL12713110 | 0.80 | CALCA (0.46) | EPHX2MC4RMC5RMC3RMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004604-B1 | SUBSTITUTED PHENYLPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS | SANTHERA PHARMACEUTICALS CH (CH) | 2010-12-01 | — | — | EP | disclosed |