Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1300303 | 1.00 | HPGD (1.00) | HPGD | |
| SCHEMBL934601 | 0.99 | HPGD (1.00) | HPGD | |
| SCHEMBL934602 | 0.99 | HPGD (1.00) | HPGD | |
| SCHEMBL1299962 | 0.94 | HPGD (1.00) | HPGD | |
| SCHEMBL1299961 | 0.94 | HPGD (1.00) | HPGD | |
| SCHEMBL1300310 | 0.93 | HPGD (1.00) | HPGD | |
| SCHEMBL1300311 | 0.93 | HPGD (1.00) | HPGD | |
| SCHEMBL1300127 | 0.91 | HPGD (1.00) | HPGD | |
| SCHEMBL1300125 | 0.91 | HPGD (1.00) | HPGD | |
| SCHEMBL1299268 | 0.87 | HPGD (1.00) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250002919-A1 | REGENERATION OR REJUVENATION OF TISSUES AND ORGANS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2025-01-02 | — | — | US | disclosed |
| US-20240423964-A1 | METHODS AND COMPOSITIONS FOR IMPROVING NEUROMUSCULAR JUNCTION MORPHOLOGY AND FUNCTION | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2024-12-26 | — | — | US | disclosed |
| EP-4419658-A1 | METHODS AND COMPOSITIONS FOR IMPROVING NEUROMUSCULAR JUNCTION MORPHOLOGY AND FUNCTION | The Board of Trustees of the Leland Stanford Junior University (US) | 2024-08-28 | — | — | EP | disclosed |
| CN-118139975-A | Methods and compositions for improving neuromuscular junction morphology and function | 莱兰斯坦福初级大学评议会 | 2024-06-04 | — | — | CN | disclosed |
| US-20240100027-A1 | INHIBITION OF PROSTAGLANDIN DEGRADING ENZYME 15-PGDH TO IMPROVE JOINT STRUCTURE AND FUNCTION | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2024-03-28 | — | — | US | disclosed |
| US-20240000758-A1 | ELEVATION OF MITOCHONDRIAL BIOGENESIS AND FUNCTION BY INHIBITION OF PROSTAGLANDIN DEGRADING ENZYME 15-PGDH | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2024-01-04 | — | — | US | disclosed |
| EP-4259154-A1 | INHIBITION OF PROSTAGLANDIN DEGRADING ENZYME 15-PGDH TO IMPROVE JOINT STRUCTURE AND FUNCTION | The Board of Trustees of the Leland Stanford Junior University (US) | 2023-10-18 | — | — | EP | disclosed |
| CN-116829155-A | Inhibition of prostaglandin degrading enzyme 15-PGDH to improve joint structure and function | 莱兰斯坦福初级大学评议会 | 2023-09-29 | — | — | CN | disclosed |
| EP-4232026-A1 | ELEVATION OF MITOCHONDRIAL BIOGENESIS AND FUNCTION BY INHIBITION OF PROSTAGLANDIN DEGRADING ENZYME 15-PGDH | The Board of Trustees of the Leland Stanford Junior University (US) | 2023-08-30 | — | — | EP | disclosed |
| CN-116457014-A | Mitochondrial biosynthesis and function enhancement by inhibition of prostaglandin degrading enzyme 15-PGDH | 莱兰斯坦福初级大学评议会 | 2023-07-18 | — | — | CN | disclosed |
| US-20220304992-A1 | METHODS OF REJUVENATING AGED TISSUE BY INHIBITING 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE (15-PGDH) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2022-09-29 | — | — | US | disclosed |
| WO-2022126125-A1 | INHIBITION OF PROSTAGLANDIN DEGRADING ENZYME 15-PGDH TO IMPROVE JOINT STRUCTURE AND FUNCTION | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2022-06-16 | — | — | WO | disclosed |
| WO-2022087631-A1 | ELEVATION OF MITOCHONDRIAL BIOGENESIS AND FUNCTION BY INHIBITION OF PROSTAGLANDIN DEGRADING ENZYME 15-PGDH | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2022-04-28 | — | — | WO | disclosed |
| EP-3982957-A1 | METHODS OF REJUVENATING AGED TISSUE BY INHIBITING 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE (15-PGDH) | The Board of Trustees of the Leland Stanford Junior University (US) | 2022-04-20 | — | — | EP | disclosed |
| CN-114206337-A | Method for rejuvenating aged tissue by inhibiting 15-hydroxyprostaglandin dehydrogenase (15-PGDH) | 莱兰斯坦福初级大学评议会 | 2022-03-18 | — | — | CN | disclosed |
| WO-2020252146-A1 | METHODS OF REJUVENATING AGED TISSUE BY INHIBITING 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE (15-PGDH) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2020-12-17 | — | — | WO | disclosed |
| EP-2383263-B1 | NOVEL THIAZOLIDINEDIONE DERIVATIVE AND USE THEREOF | UNIV CHOSUN IACF (KR) | 2014-04-16 | — | — | EP | disclosed |
| US-8637558-B2 | Thiazolidinedione derivative and use thereof | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, CHOSUN UNIVERSITY (KR) | 2014-01-28 | — | — | US | disclosed |
| US-20110269954-A1 | NOVEL THIAZOLIDINEDIONE DERIVATIVE AND USE THEREOF | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, CHOSUN UNIVERSITY (KR) | 2011-11-03 | — | — | US | disclosed |
| EP-2383263-A2 | NOVEL THIAZOLIDINEDIONE DERIVATIVE AND USE THEREOF | Industry-academic Cooperation Foundation, Chosun University (KR) | 2011-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269954-A1 | NOVEL THIAZOLIDINEDIONE DERIVATIVE AND USE THEREOF | HPGD, CYP27B1, GCDH | HPGD 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.