Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 5/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.32 |
| ▸ | GIPR | P48546 | 3/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.31 |
| ▸ | GLP1R | P43220 | 1/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | WNT1 | P04628 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2252405 | 0.80 | GCGR (0.46) | GCGRHDAC1GIPRKCNH2 | |
| SCHEMBL2667606 | 0.71 | GCGR (0.38) | GCGRACKR3HDAC1GIPR | |
| SCHEMBL2253932 | 0.70 | GCGR (0.48) | GCGRHDAC1GIPRKCNH2 | |
| SCHEMBL2667899 | 0.70 | GCGR (0.44) | GCGRACKR3HDAC1GIPRKCNH2 | |
| SCHEMBL2667900 | 0.69 | GCGR (0.59) | GCGRGIPRKCNH2 | |
| SCHEMBL13003191 | 0.67 | GCGR (0.56) | GCGRGIPRKCNH2 | |
| SCHEMBL2253874 | 0.66 | GCGR (0.42) | GCGRGIPR | |
| SCHEMBL2255779 | 0.63 | GCGR (0.59) | GCGRHDAC1GIPRKCNH2 | |
| SCHEMBL2254585 | 0.63 | GCGR (0.59) | GCGRHDAC1GIPRKCNH2 | |
| SCHEMBL12360305 | 0.62 | GCGR (0.60) | GCGRHDAC1GIPRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590336-B1 | SUBSTITUTED PYRAZOLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK SHARP & DOHME (US) | 2010-12-01 | — | — | EP | disclosed |