Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | NOS1 | P29475 | 3/20 | 0.39 |
| ▸ | NOS2 | P35228 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | LSS | P48449 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 2/20 | 0.36 |
| ▸ | FNTB | P49356 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22542152 | 0.79 | SLC6A2 (0.42) | HTR6SLC6A4SLC6A2SLC6A3HTR1A | |
| SCHEMBL20883813 | 0.76 | HTR1D (0.38) | HTR6SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL12737350 | 0.75 | SLC6A4 (0.48) | HTR6SLC6A4SLC6A2SLC6A3HTR1A | |
| SCHEMBL12737348 | 0.73 | KCNH2 (0.41) | HTR6KCNH2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL12738170 | 0.72 | HRH3 (0.41) | HTR6KCNH2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL12737970 | 0.71 | SLC6A2 (0.40) | HTR6NOS1NOS2SLC6A4SLC6A2 | |
| SCHEMBL21216508 | 0.70 | LSS (0.55) | LSSSLC6A4SLC6A2L3MBTL1 | |
| SCHEMBL724315 | 0.69 | KMT2A (0.41) | HTR6KCNH2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL13941325 | 0.69 | HTR6 (0.40) | HTR6NOS1NOS2KCNH2SLC6A4 | |
| SCHEMBL22542136 | 0.68 | HTR2C (0.49) | HTR6SLC6A4SLC6A2SLC6A3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004604-B1 | SUBSTITUTED PHENYLPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS | SANTHERA PHARMACEUTICALS CH (CH) | 2010-12-01 | — | — | EP | disclosed |