Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15314575 | 0.91 | — | — | |
| SCHEMBL24477568 | 0.82 | — | — | |
| SCHEMBL15038017 | 0.82 | — | — | |
| SCHEMBL20231523 | 0.77 | — | — | |
| SCHEMBL12835942 | 0.76 | — | — | |
| SCHEMBL21377069 | 0.76 | — | — | |
| SCHEMBL18925009 | 0.76 | — | — | |
| SCHEMBL8298097 | 0.74 | HRH3 (0.40) | HSD11B1 | |
| SCHEMBL8298892 | 0.73 | SMN1; SMN2 (0.39) | HSD11B1DPP4DPP7 | |
| SCHEMBL4532968 | 0.73 | HSD11B1 (0.36) | HSD11B1DPP4DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004604-B1 | SUBSTITUTED PHENYLPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS | SANTHERA PHARMACEUTICALS CH (CH) | 2010-12-01 | — | — | EP | disclosed |