Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 18/20 | 0.49 |
| ▸ | GIPR | P48546 | 10/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13003080 | 0.87 | GCGR (0.48) | GCGRGIPR | |
| SCHEMBL9071600 | 0.86 | GCGR (0.67) | GCGRGIPR | |
| SCHEMBL13003341 | 0.85 | GCGR (0.55) | GCGRGIPR | |
| SCHEMBL2250235 | 0.81 | GCGR (0.73) | GCGRGIPR | |
| SCHEMBL12360090 | 0.81 | GCGR (0.73) | GCGRGIPR | |
| SCHEMBL12360094 | 0.78 | GCGR (0.69) | GCGRGIPR | |
| SCHEMBL2255025 | 0.78 | GCGR (0.69) | GCGRGIPR | |
| SCHEMBL2254559 | 0.74 | GCGR (0.78) | GCGRGIPR | |
| SCHEMBL2667524 | 0.74 | GCGR (0.78) | GCGRGIPR | |
| SCHEMBL2667420 | 0.70 | GCGR (0.74) | GCGRGIPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590336-B1 | SUBSTITUTED PYRAZOLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK SHARP & DOHME (US) | 2010-12-01 | — | — | EP | disclosed |