SCHEMBL130032

SCHEMBL130032

[CH2]CCCCCCCCCC=C

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.55
ABCC4 O15439 1/20 0.46
MAPT P10636 1/20 0.46
ALDH1A1 P00352 4/20 0.45
TRPA1 O75762 3/20 0.42
TDP1 Q9NUW8 2/20 0.40
USP2 O75604 1/20 0.40
HPGD P15428 1/20 0.40
LPAR3 Q9UBY5 2/20 0.39
LMNA P02545 2/20 0.39
LPAR2 Q9HBW0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1453002 1.00 TSHR (0.55) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL131648 1.00 TSHR (0.55) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL129429 1.00 TSHR (0.55) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL130045 1.00 TSHR (0.55) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL20503164 1.00 TSHR (0.55) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL127964 1.00 TSHR (0.55) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL1454994 1.00 TSHR (0.55) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL1452859 1.00 TSHR (0.55) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL1005861 1.00 TSHR (0.55) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL131546 1.00

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112724088-A Uracil compound and anti-tumor application thereof 中国医学科学院医药生物技术研究所 2021-04-30 CN claimed
CN-112618550-A Antineoplastic uracil compound and lipid composition thereof 中国医学科学院医药生物技术研究所 2021-04-09 CN claimed
CN-107001532-B Copolymer and aqueous coating composition using same 株式会社ADEKA 2020-11-20 CN claimed
EP-1459626-B1 Sustained release dispenser comprising two or more sex pheromone substances and a pest control method SHINETSU CHEMICAL CO (JP) 2020-01-29 EP claimed
EP-3161026-B1 PHOSPHONIC COPOLYMER AND USE THEREOF IN THE COSMETICS FIELD OREAL (FR) 2018-10-10 EP claimed
EP-2365950-B1 PRODUCTION OF PHEROMONES AND FRAGRANCES FROM SUBSTITUTED AND UNSUBSTITUTED 1-ALKEN-3-YL ALKYLATES BEDOUKIAN RES INC (US) 2014-10-29 EP claimed
EP-1221836-B1 NOVEL BISEXUAL ATTRACTANTS, AGGREGANTS AND ARRESTANTS FOR ADULTS AND LARVAE OF CODLING MOTH AND OTHER SPECIES OF LEPIDOPTERA TRECE INC (US) 2010-01-20 EP claimed
US-5380462-A Cyclohexyl alkenoate compounds HOFFMANN-LA ROCHE INC. (US) 1995-01-10 US claimed
EP-0047261-B1 STABILISED COMPOSITIONS CONTAINING BEHAVIOUR MODIFYING COMPOUNDS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-06-20 EP claimed
US-12043674-B2 Synthetic cyclic peptides and methods of preparation and use thereof AUBURN UNIVERSITY (US) 2024-07-23 US disclosed
US-20240239786-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF CANCER YALE UNIVERSITY 2024-07-18 US disclosed
CN-113195441-B Androgen receptor modulators and methods of use thereof 埃萨制药股份有限公司 2024-07-12 CN disclosed
WO-2024148308-A1 NOVEL, REVERSIBLE DPP1 INHIBITORS AND USES THEREOF INSMED INCORPORATED (US) 2024-07-11 WO disclosed
WO-2024148267-A1 HETEROCYCLIC PROPYL AMINE MODULATORS OF MONOAMINERGIC TRANSPORTERS EMPATHBIO, INC. (US) 2024-07-11 WO disclosed
US-4032647-A HYPOLIPIDEMIC AGENTS RICHARDSON-MERRELL INC. (US) 1977-06-28 US disclosed
US-4017514-A Hypolipidemic agents RICHARDSON-MERRELL INC. (US) 1977-04-12 US disclosed
US-4013774-A INSECTICIDAL N-THIO-SUBSTITUTED CARBAMATES OF DIHYDROBENZOFURANOLS CHEVRON RESEARCH COMPANY (US) 1977-03-22 US disclosed
US-4011334-A USE OF SUBSTITUTED FURAN AND THIOPHENE CARBOXALDEHYDES AS HYPOLIPIDEMIC AGENTS RICHARDSON-MERRELL INC. (US) 1977-03-08 US disclosed
US-4011333-A SUBSTITUTED THIOPHENECARBOXYLIC ACID AND ESTERS AS HYPOLIPIDEMIC AGENTS RICHARDSON-MERRELL INC. (US) 1977-03-08 US disclosed
US-4000164-A SUBSTITUTED FUROYLACETIC ACIDS AND ESTERS RICHARDSON-MERRELL INC. (US) 1976-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12043674-B2 Synthetic cyclic peptides and methods of preparation and use thereof VIP, PTMS, IAPP TSHR 2949/4885ABCC4 4760/4885MAPT 4013/4885
US-20240239786-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF CANCER BRCA1, RAD51, PARP3 TSHR 2821/4885ABCC4 1706/4885MAPT 4621/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.