SCHEMBL130045

SCHEMBL130045

[CH2]CCCCCCCC=C

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.55
ABCC4 O15439 1/20 0.46
MAPT P10636 1/20 0.46
ALDH1A1 P00352 4/20 0.45
TRPA1 O75762 3/20 0.42
TDP1 Q9NUW8 2/20 0.40
USP2 O75604 1/20 0.40
HPGD P15428 1/20 0.40
LPAR3 Q9UBY5 2/20 0.39
LMNA P02545 2/20 0.39
LPAR2 Q9HBW0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1453002 1.00 TSHR (0.55) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL131648 1.00 TSHR (0.55) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL129429 1.00 TSHR (0.55) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL130032 1.00 TSHR (0.55) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL20503164 1.00 TSHR (0.55) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL127964 1.00 TSHR (0.55) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL1454994 1.00 TSHR (0.55) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL1452859 1.00 TSHR (0.55) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL1005861 1.00 TSHR (0.55) TSHRABCC4MAPTALDH1A1TRPA1
SCHEMBL131546 1.00

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4151 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240197243-A1 FRAGRANCE FOR IMPROVING RELAXATION STATE AND METHOD OF ASSESSING GIVAUDAN SA (CH) 2024-06-20 US claimed
EP-4347757-A1 FRAGRANCE FOR IMPROVING RELAXATION STATE AND METHOD OF ASSESSING Givaudan SA (CH) 2024-04-10 EP claimed
CN-117396590-A Perfume for improving relaxation state and evaluation method 奇华顿股份有限公司 2024-01-12 CN claimed
CN-116482153-A Imidazoline compound content testing method 中国石油天然气股份有限公司 2023-07-25 CN claimed
US-20230227500-A1 NANOPARTICLE-LIKE DELIVERY SYSTEM EVOX THERAPEUTICS LTD (GB) 2023-07-20 US claimed
US-20230024269-A1 Pro-Perfume Compositions FIRMENICH SA (CH) 2023-01-26 US claimed
WO-2022234149-A1 FRAGRANCE FOR IMPROVING RELAXATION STATE AND METHOD OF ASSESSING GIVAUDAN SA (CH) 2022-11-10 WO claimed
EP-4061829-A1 NANOPARTICLE-LIKE DELIVERY SYSTEM Evox Therapeutics Ltd (GB) 2022-09-28 EP claimed
CN-115038712-A Nanoparticle-like delivery system 医福斯治疗有限公司 2022-09-09 CN claimed
EP-4034073-A1 PRO-PERFUME COMPOSITIONS Firmenich SA (CH) 2022-08-03 EP claimed
EP-0219720-A2 Silicone release coatings containing higher alkenyl functional siloxanes DOW CORNING CORPORATION (US) 1987-04-29 EP claimed
EP-0217334-A2 Radiation-curable organopolysiloxane coating composition DOW CORNING CORPORATION (US) 1987-04-08 EP claimed
EP-0217333-A2 Resinous copolymeric siloxanes containing alkenyldimethylsiloxanes DOW CORNING CORPORATION (US) 1987-04-08 EP claimed
US-4611042-A Resinous copolymeric siloxanes containing alkenyldimethylsiloxanes DOW CORNING CORPORATION (US) 1986-09-09 US claimed
US-4609574-A METAL-CATALYZED HYDROSILATION DOW CORNING CORPORATION (US) 1986-09-02 US claimed
US-4596720-A Radiation-curable organopolysiloxane coating composition DOW CORNING CORPORATION (US) 1986-06-24 US claimed
US-RE31342-E STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1983-08-09 US claimed
US-4200750-A ANTIINFLAMMATORY AGENTS, FUNGICIDES, ANTIBODY INHIBITORS WESTWOOD PHARMACEUTICALS INC. (US) 1980-04-29 US claimed
US-4191767-A Method for treating fungal infection in mammals with imidazo [1,2-a]quinoxalines WESTWOOD PHARMACEUTICALS, INC. (US) 1980-03-04 US claimed
US-4172947-A IMMUNOSUPRESSANTS, AMTIIMFLAMMATORY AGENTS, FUNGICIDES WESTWOOD PHARMACEUTICALS, INC. (US) 1979-10-30 US claimed