Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 6/20 | 0.61 |
| ▸ | GNAO1 | P09471 | 6/20 | 0.61 |
| ▸ | GNAI1 | P63096 | 6/20 | 0.61 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13003345 | 0.92 | GNAI3 (0.51) | GNAI3GNAO1GNAI1EPHX1SIGMAR1 | |
| SCHEMBL13003352 | 0.84 | GNAI3 (0.43) | GNAI3GNAO1GNAI1EPHX1SIGMAR1 | |
| SCHEMBL13003347 | 0.82 | GNAI3 (0.40) | GNAI3GNAO1GNAI1EPHX1SIGMAR1 | |
| SCHEMBL9678249 | 0.79 | GNAI3 (0.94) | GNAI3GNAO1GNAI1EPHX1MEN1 | |
| SCHEMBL3868646 | 0.77 | GNAI3 (0.97) | GNAI3GNAO1GNAI1EPHX1MEN1 | |
| SCHEMBL3868605 | 0.77 | GNAI3 (0.97) | GNAI3GNAO1GNAI1EPHX1MEN1 | |
| SCHEMBL6381974 | 0.77 | GNAI3 (0.97) | GNAI3GNAO1GNAI1EPHX1MEN1 | |
| SCHEMBL13459399 | 0.77 | GNAI3 (0.84) | GNAI3GNAO1GNAI1EPHX1POLB | |
| SCHEMBL9000960 | 0.77 | SMN1; SMN2 (0.50) | EPHX1SIGMAR1SMN1; SMN2 | |
| SCHEMBL13003349 | 0.76 | GNAI3 (0.40) | GNAI3GNAO1GNAI1EPHX1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010149684-A1 | NEW COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS RELATING THERETO | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-12-29 | — | — | WO | disclosed |