Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14781349 | 0.77 | NUDT1 (0.38) | — | |
| SCHEMBL3197662 | 0.77 | MEN1 (0.39) | — | |
| SCHEMBL17011477 | 0.74 | CYP11B1 (0.31) | — | |
| SCHEMBL26288026 | 0.74 | GLP1R (0.33) | PDK2PDK4 | |
| SCHEMBL12413946 | 0.74 | CYP1A2 (0.39) | — | |
| SCHEMBL29890134 | 0.72 | — | — | |
| SCHEMBL12440989 | 0.72 | — | — | |
| SCHEMBL7251854 | 0.72 | — | — | |
| SCHEMBL17425822 | 0.71 | CCR1 (0.37) | — | |
| SCHEMBL3252967 | 0.68 | CHEK1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010149684-A1 | NEW COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS RELATING THERETO | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-12-29 | — | — | WO | disclosed |