⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1355916 | 0.80 | — | — | |
| SCHEMBL20438385 | 0.80 | ALDH1A1 (0.39) | — | |
| SCHEMBL2184765 | 0.77 | — | — | |
| SCHEMBL8415485 | 0.77 | — | — | |
| SCHEMBL12304286 | 0.72 | ALDH1A1 (0.35) | — | |
| SCHEMBL141145 | 0.72 | ALDH1A1 (0.42) | — | |
| SCHEMBL20438389 | 0.72 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL129169 | 0.72 | — | — | |
| SCHEMBL5842489 | 0.72 | ALDH1A1 (0.42) | — | |
| SCHEMBL5842275 | 0.72 | IGLV6-57 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3400231-A1 | AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING MICROBIAL INFECTIONS | Technion Research & Development Foundation Limited (IL) | 2018-11-14 | — | — | EP | claimed |
| EP-3344641-A1 | AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING GENETIC DISORDERS | Eloxx Pharmaceuticals Ltd. (IL) | 2018-07-11 | — | — | EP | claimed |
| WO-2017118967-A1 | AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING MICROBIAL INFECTIONS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2017-07-13 | — | — | WO | claimed |
| WO-2017037719-A1 | AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING GENETIC DISORDERS | ELOXX PHARMACEUTICALS LTD. (IL) | 2017-03-09 | — | — | WO | claimed |
| US-20230181612-A1 | AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING GENETIC DISORDERS | ELOXX PHARMACEUTICALS LTD. (IL) | 2023-06-15 | — | — | US | disclosed |
| US-11613551-B2 | Aminoglycoside derivatives and uses thereof in treating genetic disorders | ELOXX PHARMACEUTICALS LTD. (IL) | 2023-03-28 | — | — | US | disclosed |
| CN-114957357-A | Aminoglycoside derivatives and their use in the treatment of genetic disorders | ELOXX制药有限公司 | 2022-08-30 | — | — | CN | disclosed |
| US-20210300958-A1 | AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING GENETIC DISORDERS | ELOXX PHARMACEUTICALS LTD. (IL) | 2021-09-30 | — | — | US | disclosed |
| US-10899785-B2 | Aminoglycoside derivatives and uses thereof in treating genetic disorders | ELOXX PHARMACEUTICALS LTD. (IL) | 2021-01-26 | — | — | US | disclosed |
| EP-3634973-A1 | AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING GENETIC DISORDERS | Eloxx Pharmaceuticals Ltd. (IL) | 2020-04-15 | — | — | EP | disclosed |
| US-20190016746-A1 | AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING GENETIC DISORDERS | ELOXX PHARMACEUTICALS LTD. (IL) | 2019-01-17 | — | — | US | disclosed |
| US-20190016745-A1 | AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING MICROBIAL INFECTIONS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2019-01-17 | — | — | US | disclosed |
| EP-0275381-B1 | DYE TRANSFER PROCESS | BASF Aktiengesellschaft (DE) | 1992-03-04 | — | — | EP | disclosed |
| EP-0275381-A2 | Dye transfer process | BASF Aktiengesellschaft (DE) | 1988-07-27 | — | — | EP | disclosed |
| US-4760049-A | Dye transfer | BASF AKTIENGESELLSCHAFT (DE) | 1988-07-26 | — | — | US | disclosed |
| US-4652648-A | STABILIZERS FOR HEAT, OXIDATION AND LIGHT | CIBA-GEIGY CORPORATION (US) | 1987-03-24 | — | — | US | disclosed |
| US-4579682-A | HEAT, OXYGEN, AND LIGHT PROTECTION FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1986-04-01 | — | — | US | disclosed |
| EP-0042359-B1 | PHOSPHONOUS-ACID MONOESTER MONOAMIDE AND ORGANIC POLYMERS STABILIZED THEREWITH | CIBA-GEIGY AG (CH) | 1984-10-31 | — | — | EP | disclosed |
| US-4434109-A | STABILIZERS AGAINST HEAT, OXYGEN AND LIGHT | CIBA-GEIGY CORPORATION (US) | 1984-02-28 | — | — | US | disclosed |
| EP-0042359-A1 | Phosphonous-acid monoester monoamide and organic polymers stabilized therewith | CIBA-GEIGY AG (CH) | 1981-12-23 | — | — | EP | disclosed |