Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1300355 | 0.79 | TET2 (0.44) | TET2ALDH1A1TSHRHMGCRCHRM1 | |
| SCHEMBL6668200 | 0.77 | TET2 (0.50) | TET2ALDH1A1TSHRHMGCRCHRM1 | |
| SCHEMBL10056680 | 0.77 | TET2 (0.60) | TET2ALDH1A1TSHRHMGCRCHRM1 | |
| SCHEMBL126086 | 0.77 | TET2 (0.60) | TET2ALDH1A1TSHRHMGCRCHRM1 | |
| SCHEMBL8184932 | 0.77 | TET2 (0.39) | TET2ALDH1A1TSHRHMGCRCHRM1 | |
| SCHEMBL2582850 | 0.76 | TET2 (0.41) | TET2ALDH1A1TSHRHMGCRCHRM1 | |
| SCHEMBL10388973 | 0.71 | DGAT1 (0.37) | TET2ALDH1A1EGLN1 | |
| Pyruvate SCHEMBL1131244 | 0.71 | TET2 (0.54) | TET2ALDH1A1TSHRHMGCRCHRM1 | |
| SCHEMBL346880 | 0.71 | HMGCR (0.60) | TET2ALDH1A1TSHRHMGCRCHRM1 | |
| SCHEMBL29816178 | 0.71 | HMGCR (0.60) | TET2ALDH1A1TSHRHMGCRCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9023636-B2 | Microorganisms and methods for the biosynthesis of propylene | GENOMATICA, INC. (US) | 2015-05-05 | — | — | US | disclosed |
| US-8617862-B2 | Microorganisms for producing propylene and methods related thereto | GENOMATICA, INC. (US) | 2013-12-31 | — | — | US | disclosed |
| US-20120329119-A1 | MICROORGANISMS FOR PRODUCING PROPYLENE AND METHODS RELATED THERETO | GENOMATICA, INC. | 2012-12-27 | — | — | US | disclosed |
| US-20110269204-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF PROPYLENE | AGAIN BIO APS (DK) | 2011-11-03 | — | — | US | disclosed |