SCHEMBL13006705

SCHEMBL13006705

CCCCCCCCCCC(C)(CCCCCCCC)c1ccc(Nc2ccccc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.43
ALDH1A1 P00352 5/20 0.43
MAPK1 P28482 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
GAA P10253 5/20 0.42
ALOX12 P18054 3/20 0.42
HSD17B10 Q99714 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
PTGS1 P23219 1/20 0.42
SLC6A2 P23975 1/20 0.42
PTGS2 P35354 1/20 0.42
HTR2B P41595 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
KCNH3 Q9ULD8 1/20 0.42
HPGD P15428 4/20 0.41
HDAC3 O15379 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13006703 0.93 CNR2 (0.41) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL501958 0.85 CNR2 (0.49) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL18479352 0.84 CYP2C19 (0.44) MAPK1MEN1KMT2ASMN1; SMN2GAA
SCHEMBL3092364 0.83 CYP2C19 (0.42) MEN1KMT2AGAATDP1CNR2
SCHEMBL13006702 0.81 LMNA (0.35) MAPTALDH1A1MAPK1MEN1KMT2A
Ethane SCHEMBL21837210 0.81 CYP2C19 (0.44) MAPK1MEN1KMT2AGAACNR2
Diphenylamine SCHEMBL28868778 0.80 HSD17B10 (0.60) MAPTALDH1A1MAPK1MEN1KMT2A
Diphenylamine SCHEMBL27507095 0.80 HSD17B10 (0.60) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL30108338 0.80 MAPT (0.46) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL13006709 0.79 LMNA (0.36) MAPTALDH1A1MAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7847030-B2 Diphenylamine functionalization of poly-α-olefins EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2010-12-07 US disclosed
US-7847030-B2 Diphenylamine functionalization of poly-α-olefins EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2010-12-07 US disclosed
WO-2009108369-A2 DIPHENYLAMINE FUNCTIONALIZATION OF POLY-α-OLEFINS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2009-09-03 WO disclosed
US-20090221760-A1 Diphenylamine functionalization of poly-alpha-olefins EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2009-09-03 US disclosed
US-20090221760-A1 Diphenylamine functionalization of poly-alpha-olefins EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2009-09-03 US disclosed